Genetic guidance for understanding autism and related disorders
Autism Genomics Sweden - AuGeS - Genetic Information and Guidance in Autism and Related Psychiatric Conditions Trial
This study tests if a genetic counseling session can help young people with autism and related disorders feel more informed and empowered compared to just reading a leaflet about genetics.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 15 Years to 30 Years |
| Sex | All |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT06740760 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the impact of genetic information on adolescents and young adults with autism and related psychiatric disorders. Participants will be randomly assigned to receive either a 1.5-hour genetic counseling session with a clinician or general genetic information via a leaflet. The study aims to measure changes in understanding, well-being, and empowerment using pre- and post-intervention questionnaires. Additionally, it will explore how mental health factors like anxiety and depression influence the effectiveness of the genetic counseling intervention.
Who should consider this trial
Good fit: Ideal candidates are adolescents and young adults aged 15 to 30 living in Sweden who are interested in receiving genetic counseling information about autism.
Not a fit: Patients who are unwilling to complete pre- or post-intervention surveys or participate in genetic counseling may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and well-being of patients with autism and related disorders through informed genetic counseling.
How similar studies have performed: Other studies have shown that genetic counseling can improve understanding and empowerment in similar populations, suggesting a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants aged 15 - 30 years of age. * Living in Sweden. * Able to consent independently or with guardian consent if necessary. * Understanding of Swedish-language questions. * Interest in receiving genetic counselling information on autism. Exclusion Criteria: * Participants unwilling to complete pre- or post-intervention surveys. * Participants unwilling to participate in either form of genetic counseling
Where this trial is running
Stockholm
- Karolinska Institutet — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Kristiina Tammimies, PhD — Karolinska Institutet
- Study coordinator: Samuelle F Falk, MD
- Email: samuelle.fajutrao.falk@ki.se
- Phone: +46702495764
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.