Genetic assessment of young athletes who experience sudden cardiac arrest during sports

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry focuses on young individuals aged 12 to 35 who suffer from sudden cardiac arrest (SCA) or sudden cardiac death (SCD) related to sports activities. The study aims to identify the underlying causes of these events through comprehensive etiological assessments, including autopsies, whole exome genetic analysis, and toxicological testing. By understanding the genetic factors involved, the study seeks to provide insights that could help prevent similar incidents in family members of victims. The findings will contribute to a better understanding of the risks associated with sports participation in young athletes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Victims of SCA:

  * Aged between 12 and 35 years
  * No known cardiovascular pathology
  * Experienced a sudden and non-traumatic SCA during or within one hour of participating in sports activities (leisure, training, or competition)
  * For resuscitated victims (SCA group): A person or legal representative who does not oppose participation in the research after being informed about the study (including individuals, organs, or authorities responsible for assisting or representing them if they are unable to express their wishes).
  * For non-resuscitated victims (SCD group): A person who has not formally objected to the reuse of their medical data during their lifetime.
* First-Degree Relatives:

  * A person or legal representative who does not oppose participation in the research after being informed about the study (including individuals, bodies, or authorities responsible for assisting or representing them if they are unable to express their wishes).

Non-Inclusion Criteria:

* For resuscitated SCA cases, individuals weighing less than 20 kg
* Victims or legal representatives who are subject to legal protection or deprived of their liberty

Where it's running

• APHP Hôpital Européen Georges Pompidou
  Paris, France, France Recruiting
• CHU Rennes
  Rennes, France, France Recruiting
• CHU Bordeaux
  Bordeaux, France Recruiting
• CHU Caen
  Caen, France Recruiting
• CHU Clermont-Ferrand
  Clermont-Ferrand, France Recruiting
• CHRU Lille
  Lille, France Recruiting

Study contacts

• Principal investigator: Frédéric SCHNELL — Study Principal Investigator
• Study coordinator: Frédéric SCHNELL
• Email: frederic.schnell@chu-rennes.fr
• Phone: 0299284133

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.