Clinical trial Recruiting at 1 site Interventional Ages 18 and up

FRONT block for recovery after total hip replacement

Official title: Effect of Femoral Rami and Obturator Nerve Trunk (FRONT) Block on Postoperative Quality of Recovery After Total Hip Arthroplasty: A Prospective Randomized Controlled Trial

Run by Konya Meram State Hospital · NCT07458360 · Data updated 2026-11-12

This trial will see if adding an ultrasound-guided FRONT block to standard pain care helps adults having elective total hip replacement recover better after surgery.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment80 (estimated)
SponsorKonya Meram State Hospital
Academic / other
Locations1 site (Konya)
StatusRecruiting
StartedApril 25, 2026
Main results expectedDecember 5, 2026
Study endsDecember 5, 2026
Registry record updatedOctober 21, 2026
Trial IDNCT07458360 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults (≥18 years) scheduled for elective total hip arthroplasty under spinal anesthesia with ASA physical status I-III who can complete the QoR-15 and have no contraindications to regional anesthesia.

Probably not a fit

Patients with contraindications to regional blocks, chronic daily opioid use, significant lower-extremity neurologic or neuromuscular disorders, or cognitive impairment preventing questionnaire completion are unlikely to benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized controlled trial comparing ultrasound-guided unilateral Femoral Rami and Obturator Nerve Trunk (FRONT) block plus standard multimodal analgesia versus standard multimodal analgesia alone in adults undergoing elective total hip arthroplasty under spinal anesthesia. The FRONT block targets sensory innervation of the anterior hip capsule and is intended to provide pain relief while preserving motor function to support early mobilization. Patients are randomized at a single center and recovery is measured using validated patient-reported outcomes such as the QoR-15 questionnaire along with standard postoperative pain and opioid consumption metrics. Key eligibility includes age ≥18, ASA I-III, and ability to complete questionnaires, with exclusions for chronic opioid use, neurologic disorders of the lower limb, coagulopathy, infection at the injection site, or contraindications to regional anesthesia.

Why it matters

Potential benefit: If successful, the FRONT block could provide better postoperative pain control and improved early recovery with less motor impairment and reduced opioid needs.

How similar studies have gone: Other regional nerve-block approaches for hip surgery have shown improved postoperative analgesia and recovery, but the FRONT block is a relatively new technique with limited direct outcome data to date.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Scheduled for total hip arthroplasty under spinal anesthesia
* American Society of Anesthesiologists (ASA) physical status I-III
* Ability to understand and complete the QoR-15 questionnaire
* Provided written informed consent

Exclusion Criteria:

* Refusal to participate
* Contraindication to spinal anesthesia or regional block
* Allergy to study medications
* Chronic opioid use (daily use for more than 3 months)
* Neurological or neuromuscular disorders affecting the lower extremities
* Infection at the injection site
* Coagulation disorders
* Cognitive impairment prevents questionnaire completion

Where it's running

  • Betul Kozanhan
    Konya, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.