Frequent active breaks for people with type 1 diabetes
The Effect of Interrupting Sitting With Regular Active Breaks on Glycaemia and Daily Insulin Dose in Sedentary People With Type 1 Diabetes
This study tests if taking regular active breaks from sitting can help people with type 1 diabetes keep their blood sugar levels more stable.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 118 (estimated) |
| Ages | 18 Years to 66 Years |
| Sex | All |
| Sponsor | Liverpool John Moores University Academic / other |
| Locations | 1 site (Liverpool) |
| Trial ID | NCT05706298 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of frequent active breaks from prolonged sitting on glycemic control in individuals with type 1 diabetes who typically lead a sedentary lifestyle. Participants will be randomly assigned to either a control group or a group that incorporates active breaks over a four-week period. The study will monitor interstitial glucose levels, insulin doses, and physical activity using remote data collection methods to ensure a natural living environment. The aim is to assess whether these breaks can help maintain blood sugar levels within the target range.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-66 with a diagnosis of type 1 diabetes for more than three years and who are sedentary for more than 10 hours a day.
Not a fit: Patients who engage in structured exercise or have significant cardiovascular issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve glycemic control and overall health for individuals with type 1 diabetes.
How similar studies have performed: While the specific approach of active breaks in this context may be novel, similar interventions targeting sedentary behavior have shown promise in other populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * T1D diagnosis more than 3 years ago * Sedentary (\> 10h per waking day sedentary (sitting or lying) * Using insulin therapy with multiple daily injections or insulin pump * Aged 18-66 (UK retirement age) * Use of Abbot FreeStyle Libre 2 fGM (\>6 weeks to avoid potential lifestyle changes as a result of sensor use) Exclusion Criteria: * Engaged in structured planned exercise (e.g. running, cycling, gym, or sports) * Pregnancy or planning to become pregnant * \<6 months postpartum or stopped breastfeeding \<1 month before recruitment * Existing cerebrovascular or cardiovascular disease * Significant history of hyperglycaemia (HbA1c \>85 mmol/mol) * History of severe hypoglycaemia requiring third party assistance within the last 3 months
Where this trial is running
Liverpool
- Liverpool John Moores University — Liverpool, United Kingdom (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.