Clinical trial Recruiting at 1 site Observational Ages 18 and up

Follow-up program for patients with head and neck cancer

Official title: Standard Follow-up Program (SFP) for Head and Neck Cancer Patients Treated With Curative Primary or Postoperative Radiotherapy or Chemoradiation (SFP Head & Neck)

Run by University Medical Center Groningen · NCT02435576 · Data updated 2026-11-12

This study is testing a new follow-up program for people with head and neck cancer to see if it can reduce side effects from radiation while still being effective in treating their cancer.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment10000 (estimated)
SponsorUniversity Medical Center Groningen
Academic / other
Drugs / interventionsradiation
Locations1 site (Groningen)
StatusRecruiting
StartedMarch 2007
Main results expectedJanuary 2025
Study endsJanuary 2028
Registry record updatedApril 15, 2024
Trial IDNCT02435576 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients scheduled for curatively intended primary or postoperative radiotherapy for head and neck cancer.

Probably not a fit

Patients who are planned for palliative radiotherapy will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to improve the quality of radiotherapy for head and neck cancer patients by implementing a Standard Follow-up Program (SFP). The program focuses on reducing radiation-induced side effects while maintaining treatment efficacy. It involves developing and validating normal tissue complication probability (NTCP) models to inform patients about risks and to optimize radiotherapy treatment planning. Additionally, the study compares new radiation delivery techniques with current standards to assess their impact on toxicity, symptoms, quality of life, and overall survival.

Why it matters

Potential benefit: If successful, this program could significantly enhance the quality of life for head and neck cancer patients by minimizing treatment-related side effects.

How similar studies have gone: Other studies have shown promise in improving patient outcomes through similar approaches, particularly in optimizing radiotherapy techniques.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients planned for curatively intended primary or postoperative radiotherapy will be included. At the first visit, patients are informed about the standard follow up program by the treating physician.

Exclusion Criteria:

* All patients planned for palliative radiotherapy will not be included in the SFP.

Where it's running

  • University Medical Center Groningen
    Groningen, Netherlands
    Recruiting

Study contacts

  • Principal investigator: J.A. Langendijk, Prof. Dr. — University Medical Center Groningen
  • Study coordinator: J.A. Langendijk, Prof. Dr.
  • Email: j.a.langendijk@umcg.nl
  • Phone: +31503615532

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Using Silverlon for head and neck patients with tracheostomies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.