Follow-up program for patients with head and neck cancer
Official title: Standard Follow-up Program (SFP) for Head and Neck Cancer Patients Treated With Curative Primary or Postoperative Radiotherapy or Chemoradiation (SFP Head & Neck)
Run by University Medical Center Groningen · NCT02435576 · Data updated 2026-11-12
This study is testing a new follow-up program for people with head and neck cancer to see if it can reduce side effects from radiation while still being effective in treating their cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | University Medical Center Groningen Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Groningen) |
| Status | Recruiting |
| Started | March 2007 |
| Main results expected | January 2025 |
| Study ends | January 2028 |
| Registry record updated | April 15, 2024 |
| Trial ID | NCT02435576 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients scheduled for curatively intended primary or postoperative radiotherapy for head and neck cancer.
✕Probably not a fit
Patients who are planned for palliative radiotherapy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to improve the quality of radiotherapy for head and neck cancer patients by implementing a Standard Follow-up Program (SFP). The program focuses on reducing radiation-induced side effects while maintaining treatment efficacy. It involves developing and validating normal tissue complication probability (NTCP) models to inform patients about risks and to optimize radiotherapy treatment planning. Additionally, the study compares new radiation delivery techniques with current standards to assess their impact on toxicity, symptoms, quality of life, and overall survival.
Why it matters
Potential benefit: If successful, this program could significantly enhance the quality of life for head and neck cancer patients by minimizing treatment-related side effects.
How similar studies have gone: Other studies have shown promise in improving patient outcomes through similar approaches, particularly in optimizing radiotherapy techniques.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients planned for curatively intended primary or postoperative radiotherapy will be included. At the first visit, patients are informed about the standard follow up program by the treating physician. Exclusion Criteria: * All patients planned for palliative radiotherapy will not be included in the SFP.
Where it's running
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University Medical Center Groningen
Groningen, Netherlands Recruiting
Study contacts
- Principal investigator: J.A. Langendijk, Prof. Dr. — University Medical Center Groningen
- Study coordinator: J.A. Langendijk, Prof. Dr.
- Email: j.a.langendijk@umcg.nl
- Phone: +31503615532
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Phenotype-based Pain Guidance for Head and Neck Cancer-Related Pain (pilot)
This pilot test sees if tailoring pain treatment to a patient’s pain type can reduce head and neck cancer pain in adults who haven’t started cancer treatment yet.
-
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In this phase 2 study, patients with locally advanced, resectable oral squamous cell carcinoma will receive a combination of iparomlimab, tuvonralimab, and cetuximab before surgery to see if the treatment is safe and can shrink tumors.
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SumMET: Targeted radioligand therapy for c-MET–positive solid tumors
This first‑in‑human study tests the safety and potential effectiveness of a radioligand therapy called [225Ac]Ac-FL-261 in adults with advanced or metastatic solid tumors that overexpress c-MET.
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Using Silverlon for head and neck patients with tracheostomies
This early-phase study tests whether Silverlon dressings can prevent severe skin reactions under tracheostomy collars in adults with head and neck cancer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.