Follow-up on mothers and children affected by gestational diabetes
EMERGE Mothers and Kids: a Longitudinal Cohort Study of Mothers and Kids Enrolled in the Randomized Placebo Controlled Trial of Metformin in Women With GDM (EMERGE)
National University of Ireland, Galway, Ireland · NCT06327191
This study follows mothers and their children who had gestational diabetes to see how metformin treatment affects their long-term health and the children's weight over the next 10 years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 321 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | National University of Ireland, Galway, Ireland (other) |
| Locations | 1 site (Galway) |
| Trial ID | NCT06327191 on ClinicalTrials.gov |
What this trial studies
The EMERGE Mothers and Kids study is a follow-up to the original EMERGE trial, which involved women with gestational diabetes. This observational study aims to assess the long-term effects of metformin treatment on maternal health outcomes, including metabolic disorders and mental health, as well as the impact on the offspring's obesity and adiposity. Participants from the original trial will be monitored for up to 10 years to gather data on various health metrics. The study does not involve any new interventions, focusing instead on the outcomes of previous treatments.
Who should consider this trial
Good fit: Ideal candidates are women who participated in the original EMERGE trial and consented to further follow-up.
Not a fit: Patients who did not participate in the original EMERGE trial or did not consent for further follow-up will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the long-term health benefits of metformin for mothers and their children affected by gestational diabetes.
How similar studies have performed: While this study builds on previous findings from the EMERGE trial, the long-term follow-up aspect is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participation in the original EMERGE trial and consenting to further follow up. Exclusion Criteria: * EMERGE trial participants who did not provide consent for further follow up studies.
Where this trial is running
Galway
- University Hospital Galway — Galway, Ireland (RECRUITING)
Study contacts
- Study coordinator: Fidelma Dunne, Prof
- Email: fidelma.dunne@universityofgalway.ie
- Phone: 091 495 964
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gestational Diabetes