Follow-up cohort for migraine patients with a heart condition
Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale
This study is testing different treatment options for migraine patients who also have a heart condition called a patent foramen ovale to see what helps them feel better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 330 (estimated) |
| Sex | All |
| Sponsor | Peking University Third Hospital Academic / other |
| Locations | 1 site (Beijing) |
| Trial ID | NCT06953622 on ClinicalTrials.gov |
What this trial studies
This study aims to establish a headache center in China that integrates clinical, imaging, and laboratory examinations for migraine patients who also have a patent foramen ovale. It will explore feasible treatment options, including conservative treatment and closure of the patent foramen ovale, while investigating factors that may influence prognosis. The study will involve a cohort of patients diagnosed with migraine according to established criteria and confirmed to have a patent foramen ovale through echocardiographic methods.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with migraine who also have a confirmed patent foramen ovale.
Not a fit: Patients who do not have a patent foramen ovale or do not meet the diagnostic criteria for migraine may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for migraine patients with patent foramen ovale, potentially reducing the frequency and severity of their headaches.
How similar studies have performed: While there have been studies exploring the relationship between migraine and patent foramen ovale, this specific approach of establishing a comprehensive cohort is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Meet the diagnostic criteria for migraine in the International Classification of Headache (ICHD-3); * Confirmation of patent foramen ovale through transthoracic echocardiography(TTE) or transesophageal echocardiography(TEE)/right heart contrast echocardiography * Agree to participate in the study and sign the informed consent form. Exclusion Criteria: * Can not sign the informed consent form or cooperate with follow-up.
Where this trial is running
Beijing
- Peking University Third Hospital — Beijing, China (Recruiting)
Study contacts
- Study coordinator: Yu Fu
- Email: lilac_fu@126.com
- Phone: 13671185050
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.