Follicular Flushing During Abdominal Egg Retrieval in Women with Low Egg Reserve

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational, two-centre study compares two abdominal oocyte retrieval techniques in women who have decided to freeze their eggs and have AMH ≤1.0 ng/mL. Centre A uses direct aspiration only, while Centre B uses systematic follicular flushing with a double-channel needle and multiple rinses if needed. The aim is to see if flushing increases the total number of eggs retrieved and the number of mature eggs suitable for freezing. All procedures are performed by experienced operators under standard stimulation protocols, and enrollment follows Turkish regulatory guidelines for oocyte cryopreservation.

Why it matters

Who can join: the full rules

IEligibility Criteria

Inclusion Criteria:

* Women aged 18-42 years
* Serum anti-Müllerian hormone (AMH) ≤1.0 ng/mL
* Planned oocyte cryopreservation for fertility preservation
* Decline of transvaginal oocyte retrieval for cultural or personal reasons, with transabdominal retrieval chosen as the preferred route
* Eligible for oocyte cryopreservation under Turkish regulations
* At least one follicle ≥17 mm on the day of ovulation trigger
* Written informed consent

Exclusion Criteria:

* Conditions that prevent safe transabdominal access, such as extensive pelvic adhesions or unfavourable ovarian position
* Previous major abdominal or pelvic surgery likely to interfere with the procedure
* Active pelvic infection
* Suspected ovarian malignancy
* Contraindications to sedation or oocyte retrieval
* Retrieval performed outside local regulatory requirements
* Incomplete clinical or laboratory data

Where it's running

• Centrum Clinic IVF Center
  Ankara, Ankara, Turkey (Türkiye) Recruiting
• Brussels IVF Center
  Istanbul, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Emre pabuçcu, Professor
• Email: emregpabuccu@gmail.com
• Phone: 05324147844

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.