Combining ovarian tissue freezing with egg (oocyte) freezing versus egg freezing alone

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project will collect clinical data from two groups of adult oncology patients facing potentially gonadotoxic treatment: those who undergo ovarian tissue cryopreservation followed by oocyte cryopreservation, and those who undergo oocyte cryopreservation alone. Investigators will compare outcomes such as number of preserved follicles, number of mature oocytes retrieved, timing relative to cancer therapy, and recovery of ovarian endocrine function. Eligible participants are women aged 18–46 with BMI between 17.5 and 32 and oncological clearance, while patients positive for HBV, HCV, HIV, or Treponema pallidum or with hypersensitivity to stimulation drugs are excluded. The study is single-center and will use routine clinical and laboratory records at the treating hospital to characterize real-world differences between the approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with oncological disease eligible for potentially gonadotoxic therapy
* BMI ≥ 17.5 kg/m² and ≤ 32 kg/m²
* Age ≥ 18 years and ≤ 46 years

Exclusion Criteria:

* Hypersensitivity to one or more of the active substances used during ovarian stimulation treatment
* Positive for HBV, HCV, HIV, or Treponema pallidum
* Lack of oncological clearance

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Bologna, Italy Recruiting

Study contacts

• Study coordinator: Diego Raimondo, MD
• Email: die.raimondo@gmail.com
• Phone: +393290636618

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.