Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Focused shock wave therapy to help recovery after ACL surgery

Official title: Effectiveness of Focused Extracorporeal Shock Wave Therapy Applied as an Addition to Conventional Physiotherapy Program After Anterior Cruciate Ligament Reconstruction

Run by Biruni University · NCT06688344 · Data updated 2026-11-12

This program will test whether adding a weekly low‑intensity focused shock wave treatment to standard physiotherapy helps adults aged 18–45 regain strength, motion, balance, and reduce pain after ACL reconstruction with a hamstring graft.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment32 (estimated)
SponsorBiruni University
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedDecember 1, 2024
Main results expectedDecember 1, 2026
Study endsMay 1, 2027
Registry record updatedDecember 19, 2025
Trial IDNCT06688344 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–45 with a unilateral, isolated ACL rupture reconstructed using a hamstring graft and no major comorbidities are the intended participants.

Probably not a fit

Patients with previous knee injuries or ACL revision, systemic inflammatory or metabolic bone diseases, recent intra‑articular injections, vascular problems in the leg, cognitive impairment, or outside the age range are unlikely to qualify or benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with a unilateral, isolated ACL rupture repaired with a hamstring graft receive a conventional physiotherapy program twice weekly. Participants are assigned to receive either conventional physiotherapy alone, conventional physiotherapy plus low‑intensity focused extracorporeal shock wave therapy once weekly, or a sham procedure alongside physiotherapy. Outcomes measured include muscle strength, postural balance, range of motion, pain scores, and functional status. The protocol tests whether adding fESWT provides measurable recovery benefits over physiotherapy alone.

Why it matters

Potential benefit: If successful, adding focused shock wave therapy could speed functional recovery and reduce pain after ACL reconstruction when combined with standard physiotherapy.

How similar studies have gone: ESWT has shown benefits for various tendon and soft‑tissue problems, but focused ESWT specifically for recovery after ACL reconstruction has limited direct evidence and remains relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 45 years
* Unilateral ACL rupture
* Isolated ACL injury
* Hamstring graft

Exclusion Criteria:

* Previous knee injury and anterior cruciate ligament revision
* Synovitis, stiffness, tension
* History of systemic diseases such as rheumatoid arthritis, osteoarthritis, osteoporosis
* Presence of tumor
* Deep vein thrombosis or vascular pathology in the lower extremity
* RA or accompanying comorbidities
* Having had intra-articular injection within 6 months
* Cognitive impairment

Where it's running

  • Istanbul Faculy of Medicine-Department of Sports Medicine
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.