Financial support for low-income heart failure patients

Financial Support in an Underserved and Low-Income Population With Heart Failure

NA · University of Texas Southwestern Medical Center · NCT05928026

This study is testing if giving low-income heart failure patients a one-time $500 payment can help them stick to their medications and feel better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorUniversity of Texas Southwestern Medical Center (other)
Locations1 site (Dallas, Texas)
Trial IDNCT05928026 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to determine if a one-time financial stipend of $500 can enhance medication adherence and improve quality of life for low-income patients with heart failure and reduced ejection fraction. Participants will be randomly assigned to receive either the stipend or no financial support at the start, and their quality of life and medication adherence will be assessed after one month. Those who initially receive no stipend will be given the financial support at the one-month mark and will return for a follow-up assessment at two months. The study focuses on the impact of financial stress on health outcomes in an underserved population.

Who should consider this trial

Good fit: Ideal candidates are English-speaking adults over 18 with heart failure, reduced ejection fraction, and significant financial stress.

Not a fit: Patients who are currently incarcerated or have legal blindness may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life and medication adherence for low-income heart failure patients.

How similar studies have performed: While financial support interventions are relatively novel in this context, similar studies have shown promise in improving health outcomes through addressing social determinants of health.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 18
* English speaking participants who completed SOCIAL-HF study surveys
* Ejection Fraction \<=40% and eligible for at least one component of GDMT
* Has at least some difficulty paying monthly bills (Somewhat Difficult and Very Difficult)
* Annual household income \<130% Federal Poverty Limit
* Have at least two additional social needs based on the following domains:

  * Cost-related nonadherence
  * Food Insecurity
  * Housing Instability
  * Transportation Difficulty
  * Unemployment
  * Household Crowding: Person/Room Ratio \>1
  * Rent Burden: Rent/Income Ratio \>30%
  * Low social support
  * Interpersonal Violence
  * History of Discrimination

Exclusion Criteria:

* Unwilling to return for 1 and 2-month follow-up visits.
* Currently in jail or prison
* Primary residence outside Dallas County
* Legal Blindness
* Systolic blood pressure \<90 mmHg on screening
* Contraindications or Intolerance all medications available for therapeutic drug monitoring (metoprolol, losartan, lisinopril, valsartan, and spironolactone)
* Unable to answer orientation questions.

Where this trial is running

Dallas, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Heart Failure, Systolic, Financial Stress, Medication Adherence, Quality of Life, social determinants of health

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.