Fertility preservation for women with endometriosis
Fertility Preservation in Case of Endometriosis : Observational Cohort Study
This study is testing whether freezing eggs can help young women with endometriosis preserve their fertility and improve their quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 36 Years |
| Sex | Female |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris, Ile De France) |
| Trial ID | NCT03744754 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to evaluate the efficacy of oocyte cryopreservation as a fertility preservation method for young women diagnosed with endometriosis. Participants will undergo ovarian stimulation, oocyte retrieval, and cryopreservation of mature oocytes, with follow-up questionnaires assessing quality of life and reproductive outcomes. The study seeks to establish eligibility criteria for fertility preservation procedures specifically tailored for women with endometriosis, addressing the unique challenges they face regarding ovarian reserve and reproductive health.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 18 to 36 with a confirmed diagnosis of endometriosis.
Not a fit: Patients who have contraindications for ovarian stimulation or pregnancy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide critical insights into fertility preservation options for women with endometriosis, potentially improving their reproductive outcomes.
How similar studies have performed: While data on fertility preservation in endometriosis patients is limited, previous studies have shown promise in related areas, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * women from 18 to 36 years old * endometriosis disease proved by sonography, MRI and/or surgery * Consenting to participate to the study Exclusion Criteria: * Any contraindication for ovarian stimulation. * Any contraindication for pregnancy .- Impossible Follow-up.
Where this trial is running
Paris, Ile De France
- Service de Gynécologie Obstétrique et Médecine de la Reproduction Hôpital TENON — Paris, Ile De France, France (Recruiting)
Study contacts
- Principal investigator: Emmanuelle Mathieu d'Argent, MD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Emmanuelle Mathieu d'Argent, MD
- Email: emmanuelle.mathieu@aphp.fr
- Phone: +33 156 01 68 69
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.