Fertility preservation for women with endometriosis
Official title: Fertility Preservation in Case of Endometriosis : Observational Cohort Study
Run by Assistance Publique - Hôpitaux de Paris · NCT03744754 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether freezing eggs can help young women with endometriosis preserve their fertility and improve their quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 36 Years |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Paris, Ile De France) |
| Trial ID | NCT03744754 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18 to 36 with a confirmed diagnosis of endometriosis.
✕Probably not a fit
Patients who have contraindications for ovarian stimulation or pregnancy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study aims to evaluate the efficacy of oocyte cryopreservation as a fertility preservation method for young women diagnosed with endometriosis. Participants will undergo ovarian stimulation, oocyte retrieval, and cryopreservation of mature oocytes, with follow-up questionnaires assessing quality of life and reproductive outcomes. The study seeks to establish eligibility criteria for fertility preservation procedures specifically tailored for women with endometriosis, addressing the unique challenges they face regarding ovarian reserve and reproductive health.
Why it matters
Potential benefit: If successful, this study could provide critical insights into fertility preservation options for women with endometriosis, potentially improving their reproductive outcomes.
How similar studies have gone: While data on fertility preservation in endometriosis patients is limited, previous studies have shown promise in related areas, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * women from 18 to 36 years old * endometriosis disease proved by sonography, MRI and/or surgery * Consenting to participate to the study Exclusion Criteria: * Any contraindication for ovarian stimulation. * Any contraindication for pregnancy .- Impossible Follow-up.
Where it's running
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Service de Gynécologie Obstétrique et Médecine de la Reproduction Hôpital TENON
Paris, Ile De France, France Recruiting
Study contacts
- Principal investigator: Emmanuelle Mathieu d'Argent, MD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Emmanuelle Mathieu d'Argent, MD
- Email: emmanuelle.mathieu@aphp.fr
- Phone: +33 156 01 68 69
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparing different techniques to treat endometriosis
This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.
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Postoperative Pain Trajectories After Endometriosis Surgery
This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.
-
Imaging endometriosis with a special PET tracer in adult women
This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.
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Fiber supplement for digestive symptoms in endometriosis
A fiber-based supplement is being tested to see if it is safe and helps with gut and vaginal microbiomes and digestive symptoms in women with endometriosis.
-
Stellate ganglion block and dexmedetomidine for better sleep after gynecologic laparoscopy
The study tests whether giving a preoperative stellate ganglion block plus intraoperative dexmedetomidine improves sleep after laparoscopic gynecologic surgery in women.
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Atypical Endometriosis: Histology, Immunophenotype and Molecular Features
Researchers will look at how endometriotic tissue that looks atypical under the microscope relates to clinical features and ultrasound findings to better separate benign from potentially atypical lesions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.