FeNO-Guided Asthma Care in Children
Official title: FeNO Fractional Exhaled Nitric Oxide Test as Significant Tool in Enhancing Asthma Treatment Management Among Children
Run by King Faisal Specialist Hospital & Research Center · NCT07788534 · Data updated 2026-11-12
This study checks if adding fractional exhaled nitric oxide (FeNO) monitoring to regular pediatric asthma care helps kids manage asthma better than a historical group not using FeNO.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 14 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | King Faisal Specialist Hospital & Research Center Academic / other |
| Locations | 2 sites (Jeddah, Mecca Region and 1 other locations) |
| Status | Recruiting |
| Started | November 12, 2025 |
| Main results expected | November 12, 2026 |
| Study ends | November 12, 2026 |
| Registry record updated | August 26, 2026 |
| Trial ID | NCT07788534 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 6–14 with physician-diagnosed asthma and at least three months of follow-up with available ACT/C-ACT data.
✕Probably not a fit
Children with asthma who do not show FeNO-related improvements or have concurrent conditions limiting FeNO utility may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares outcomes in children aged 6 to 14 with asthma who receive FeNO-guided management to a historical cohort managed without FeNO. Interventions include FeNO testing and standard pulmonary function tests, with observational elements linking FeNO levels to ACT/C-ACT scores, eosinophil counts, FEV1%, inhaled corticosteroid adherence, and exacerbation frequency. Eligible participants must have at least three months of follow-up at a pediatric respiratory clinic and available ACT/C-ACT data. Exclusions include other chronic lung diseases, recent infections, or biologic therapies affecting asthma inflammation. The study is sponsored by King Faisal Specialist Hospital & Research Center in Jeddah, Saudi Arabia.
Why it matters
Potential benefit: If successful, FeNO-guided care could improve asthma control and reduce exacerbations in children.
How similar studies have gone: Prior research with FeNO-guided management has shown mixed results; this study explores its utility against a historical comparator in pediatrics.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children aged 6 to 14 years with a physician-diagnosed asthma. * Minimum of three months' follow-up at the pediatric respiratory clinic. * Availability of Asthma Control Test (ACT/C-ACT) scores and clinical data Exclusion Criteria: * Presence of other chronic pulmonary diseases (e.g., cystic fibrosis). * Recent respiratory infections within four weeks prior to enrollment. * Current treatment with biologic agents affecting asthma inflammation.
Where it's running
-
king Faisal specialized hospital and research center
Jeddah, Western Region, Saudi Arabia Recruiting -
King Faisal Sepiclaized Hospital and Research Center
Jeddah, Mecca Region, Saudi Arabia Active not recruiting
Study contacts
- Principal investigator: Nariman Alrabie — king Faisal specialized hospital and research center
- Study coordinator: Abrar Barnawi
- Email: abarnawi1@kfshrc.edu.sa
- Phone: 966551266326
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.