Family support program to help teens with depression or anxiety who are in substance use treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This R34 project develops and pilots an adjunctive family-support protocol called Fam-AID to address co-occurring internalizing disorders in adolescents receiving community outpatient care for substance use. Fam-AID is delivered with a primary caregiver alongside usual care and is designed to be briefer and easier to scale than intensive manualized integrated models. The protocol will be tested across three U.S. clinical sites for feasibility, acceptability, and preliminary clinical effects on internalizing symptoms and substance use engagement. Eligible participants are youth aged 13–21 enrolled in outpatient substance use treatment who have current depressive or anxiety symptoms or diagnoses, while those with severe acute needs (e.g., detox, inpatient) are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Youth is age 12-20.
* Youth lives with a primary caregiver who can attend treatment sessions.
* Youth endorses one or more DSM-5-TR symptoms for SUD and meets American Society of Addiction Medicine criteria for outpatient SU treatment.
* Youth meets DSM-5-TR criteria, or has elevated symptoms and impairment, for any of the following IDs: Current or Recurrent Major Depressive Episode, Pervasive Depressive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Panic Disorder, Posttraumatic Stress Disorder.
* Youth completes intake and is enrolled as an active case at study site

Exclusion Criteria:

* Illness requiring hospitalization
* Current psychotic symptoms
* Severe SU problems that require immediate relief (detox or residential placement)
* Pervasive developmental disorder.

Where it's running

• Lurie Children's Hospital
  Chicago, Illinois, United States Recruiting
• Indiana University School of Medicine
  Indianapolis, Indiana, United States Recruiting
• Roberto Clemente Center
  New York, New York, United States Recruiting

Study contacts

• Study coordinator: Nicole P Porter, PhD
• Email: nporter@toendaddiction.org
• Phone: (212) 841-5211

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.