External oblique intercostal block versus erector spinae plane block for pain after laparoscopic radical gastrectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center, randomized non-inferiority trial compares the novel external oblique intercostal block (EOIB) with the established erector spinae plane block (ESPB) for postoperative analgesia after laparoscopic radical gastrectomy. Patients undergoing elective subtotal or total laparoscopic gastrectomy under general anesthesia are randomized to receive EOIB or ESPB and followed for postoperative pain outcomes and opioid consumption. EOIB delivers local anesthetic between the external oblique and intercostal muscles to block anterior rami and cutaneous branches of T6–T10, while ESPB targets the erector spinae plane with known variability in local anesthetic spread. The trial aims to determine whether EOIB provides pain relief that is not worse than ESPB and could offer a practical alternative for upper abdominal analgesia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged over 18 years
* Classified as ASA I-III
* Scheduled for elective laparoscopic radical gastrectomy under general anesthesia
* Voluntarily participated and provided written informed consent.

Exclusion Criteria:

* Chronic opioid dependence or prior use of analgesic medications for \>3 months;
* Inability to communicate due to severe dementia, language barriers, or terminal illness;
* History of central and/or peripheral nervous system disorders;
* Severe renal insufficiency (serum creatinine \>442 μmol/L or requiring renal replacement therapy) or severe hepatic insufficiency (Child-Pugh class C);
* Allergy to local anesthetics.
* Expected to be transferred to ICU after surgery.

Where it's running

• General hospital of Ningxia medical university
  Yinchuan, Ningxia, China Recruiting

Study contacts

• Study coordinator: Lingzi Yin, Doctoral
• Email: eleven87670@163.com
• Phone: 86-951-674-3252

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• PECS II vs SPSIP nerve blocks for pain after mastectomy

  This study tests whether two ultrasound-guided nerve blocks (PECS II and SPSIP) differ in how much opioid patients need after mastectomy.

  Recruiting Bursa City Hospital · Nilufer, Bursa · NCT07929090

• Palatal Shield Technique to Reduce Pain and Improve Healing After Free Gingival Graft

  This randomized trial tests whether a collagen sponge with a protective palatal shield made of flowable resin helps reduce pain and improve healing after free gingival graft harvest.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07926516

• Perfusion Index to Measure Postoperative Pain in Kids After Adenotonsillectomy

  This study tests whether the perfusion index can reliably reflect pain levels in children aged 1–12 after adenotonsillectomy, comparing standard care with an added glossopharyngeal nerve block.

  Recruiting Istanbul University · Istanbul, Istanbul · NCT07915804

• Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy

  This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.

  Recruiting Van Training and Research Hospital · Van · NCT07910500

• Natural Biopolymer-Based Irrigant for Root Canal Cleaning

  This trial tests a chitosan nanoparticle irrigant to improve cleaning and disinfection in single-rooted teeth with asymptomatic pulp necrosis undergoing endodontic treatment.

  Recruiting Minia University · Minya · NCT07901127

• Postoperative Pain Trajectories After Endometriosis Surgery

  This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07882498

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.