Extended follow-up of people who went to emergency care after a suicide attempt in Spain
THE SURVIVE 2 PROJECT: AN EXTENDED COHORT STUDY TO INVESTIGATE SUICIDAL BEHAVIOR IN SPAIN AND THE EFFICACY OF SECONDARY PREVENTION STRATEGIES
This project will follow people seen in Spanish emergency departments after a suicide attempt to see if personal, social, biological factors and different follow-up approaches affect the chance of trying again.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3600 (estimated) |
| Ages | 12 Years and up |
| Sex | All |
| Sponsor | Parc de Salut Mar Academic / other |
| Locations | 2 sites (Barcelona, Catalonia and 1 other locations) |
| Trial ID | NCT07554729 on ClinicalTrials.gov |
What this trial studies
This is a multicenter prospective cohort that will follow about 3,600 people (1,800 from an earlier cohort plus 1,800 newly recruited) who presented to emergency departments in Spain after a suicide attempt, with primary outcome time to repeat attempt. Participants will be followed for up to five years, with some invited to provide blood samples, complete online questionnaires, or use smartphone-based momentary assessments to capture day-to-day mood and suicidal thoughts. The project includes five nested controlled trials that will compare different secondary prevention programs against treatment as usual. Data will be collected across nine Spanish centers to identify socioeconomic, clinical, biological, and genetic risk markers and to study changes related to the pandemic period.
Who should consider this trial
Good fit: People aged 12 or older who present to participating Spanish hospital emergency departments after a suicide attempt, can provide informed consent (or assent with guardian consent for minors), and have sufficient Spanish to complete assessments are eligible.
Not a fit: Individuals whose self-harm was judged accidental or without suicidal intent, those with severe cognitive impairment or acute medical instability that prevents safe participation, or people unlikely to complete follow-up are unlikely to benefit from the study.
Why it matters
Potential benefit: If successful, this work could show who is at higher risk and which follow-up programs reduce repeat suicide attempts, helping emergency services target prevention more effectively.
How similar studies have performed: Prior cohort studies, including the earlier 1,800-person cohort this project extends, have identified risk factors for repeat attempts, but evidence on which secondary prevention programs reliably reduce repeat attempts is limited and mixed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals (above 12 years old) who present to participating Spanish hospital emergency departments after a suicide attempt, as defined by self-injurious behavior with at least some intent to die. * Able to understand the study procedures and provide informed consent (or assent with parental/guardian consent for minors, according to local regulations) * Sufficient proficiency in Spanish to complete study assessments Exclusion Criteria: * Suicide attempts clearly judged as accidental or without suicidal intent * Severe cognitive impairment, intellectual disability, or neurological condition that, in the opinion of the clinical team, prevents valid assessment or informed consent * Acute medical instability that makes participation in research procedures unsafe. * Any condition or circumstance that, in the opinion of investigators, would seriously interfere with participation or follow-up in the cohort.
Where this trial is running
Barcelona, Catalonia and 1 other locations
- Hospital del Mar — Barcelona, Catalonia, Spain (Recruiting)
- Hospital Clinic — Barcelona, Spain (Recruiting)
Study contacts
- Study coordinator: Victor Perez-Sola, Dr
- Email: vperez@psmar.cat
- Phone: +34 933160623
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.