Clinical trial Recruiting at 2 sites Observational Ages 12 and up

Extended follow-up of people who went to emergency care after a suicide attempt in Spain

Official title: THE SURVIVE 2 PROJECT: AN EXTENDED COHORT STUDY TO INVESTIGATE SUICIDAL BEHAVIOR IN SPAIN AND THE EFFICACY OF SECONDARY PREVENTION STRATEGIES

Run by Parc de Salut Mar · NCT07554729 · Data updated 2026-11-12

This project will follow people seen in Spanish emergency departments after a suicide attempt to see if personal, social, biological factors and different follow-up approaches affect the chance of trying again.

More Suicidal Behaviors trials

Quick facts

Study typeObservational
Ages12 Years and up
SexAll
Enrollment3600 (estimated)
SponsorParc de Salut Mar
Academic / other
Locations2 sites (Barcelona, Catalonia and 1 other locations)
StatusRecruiting
StartedSeptember 1, 2024
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedApril 28, 2026
Trial IDNCT07554729 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

People aged 12 or older who present to participating Spanish hospital emergency departments after a suicide attempt, can provide informed consent (or assent with guardian consent for minors), and have sufficient Spanish to complete assessments are eligible.

Probably not a fit

Individuals whose self-harm was judged accidental or without suicidal intent, those with severe cognitive impairment or acute medical instability that prevents safe participation, or people unlikely to complete follow-up are unlikely to benefit from the study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter prospective cohort that will follow about 3,600 people (1,800 from an earlier cohort plus 1,800 newly recruited) who presented to emergency departments in Spain after a suicide attempt, with primary outcome time to repeat attempt. Participants will be followed for up to five years, with some invited to provide blood samples, complete online questionnaires, or use smartphone-based momentary assessments to capture day-to-day mood and suicidal thoughts. The project includes five nested controlled trials that will compare different secondary prevention programs against treatment as usual. Data will be collected across nine Spanish centers to identify socioeconomic, clinical, biological, and genetic risk markers and to study changes related to the pandemic period.

Why it matters

Potential benefit: If successful, this work could show who is at higher risk and which follow-up programs reduce repeat suicide attempts, helping emergency services target prevention more effectively.

How similar studies have gone: Prior cohort studies, including the earlier 1,800-person cohort this project extends, have identified risk factors for repeat attempts, but evidence on which secondary prevention programs reliably reduce repeat attempts is limited and mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals (above 12 years old) who present to participating Spanish hospital emergency departments after a suicide attempt, as defined by self-injurious behavior with at least some intent to die.
* Able to understand the study procedures and provide informed consent (or assent with parental/guardian consent for minors, according to local regulations)
* Sufficient proficiency in Spanish to complete study assessments

Exclusion Criteria:

* Suicide attempts clearly judged as accidental or without suicidal intent
* Severe cognitive impairment, intellectual disability, or neurological condition that, in the opinion of the clinical team, prevents valid assessment or informed consent
* Acute medical instability that makes participation in research procedures unsafe.
* Any condition or circumstance that, in the opinion of investigators, would seriously interfere with participation or follow-up in the cohort.

Where it's running

  • Hospital del Mar
    Barcelona, Catalonia, Spain
    Recruiting
  • Hospital Clinic
    Barcelona, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.