Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Expressive writing intervention for sexual minority veterans

Official title: Expressive Writing to Reduce Depressive and Anxiety Symptoms Among Sexual Minority Veterans

Run by VA Office of Research and Development · NCT05897021 · Data updated 2026-11-12

This study tests whether a short writing program can help reduce feelings of depression and anxiety in sexual minority veterans by allowing them to express their thoughts and emotions about their experiences.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment85 (estimated)
SponsorVA Office of Research and Development
Federal
Locations1 site (Boston, Massachusetts)
StatusRecruiting
StartedMarch 20, 2024
Main results expectedOctober 1, 2027
Study endsSeptember 30, 2028
Registry record updatedFebruary 2, 2026
Trial IDNCT05897021 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are veterans who identify as sexual minorities and experience clinically significant depressive or anxiety symptoms.

Probably not a fit

Patients with current suicidal intent, unstable mania, psychosis, or severe substance use disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research examines the feasibility and effectiveness of a brief, three-session expressive writing intervention aimed at reducing depressive and anxiety symptoms among sexual minority veterans. The intervention focuses on addressing distress related to sexual minority stressors, such as discrimination and stigma. Participants will engage in structured writing exercises to explore their thoughts and emotions related to these stressors. The study aims to provide a scalable and accessible mental health intervention tailored to the unique needs of sexual minority veterans.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce depressive and anxiety symptoms in sexual minority veterans, improving their overall mental health and well-being.

How similar studies have gone: Previous studies have shown that expressive writing can effectively reduce depression and anxiety in sexual minorities, but this specific approach has not been tested among sexual minority veterans.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Participants will be Veterans who:

* identify as a sexual minority (i.e., identify as gay, lesbian, bisexual, pansexual, queer, or another identity other than heterosexual)
* endorse clinically significant depressive or anxiety symptoms (score above 10 on the PHQ-9 or GAD-7)
* report a history of sexuality-based minority stressor exposure that is contributing to distress on phone screening
* be stable on psychotropic medication for at least 4 weeks if on a psychotropic medication

Exclusion Criteria:

The exclusion criteria for Veterans in this study are:

* clear and current suicidal plan and/or intent (assessed via the Columbia Suicide Severity Rating Scale)
* current presentation of unstable mania and/or psychosis (assessed via the Structured Interview for DSM-5)
* current substance use disorder, severe (assessed via the Structured Interview for DSM-5)
* significant cognitive impairment, including evidence of moderate or severe traumatic brain injury, determined by an inability to comprehend baseline screening questionnaires

Where it's running

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
    Boston, Massachusetts, United States
    Recruiting

Study contacts

  • Principal investigator: Kelly L Harper, PhD — VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
  • Study coordinator: Kelly L Harper, PhD
  • Email: kelly.harper@va.gov
  • Phone: (857) 364-4417

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.