Exploring treatments for amblyopia in children using OCT technology

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between OCT eccentric fixation and various treatment methods for amblyopia in children. It aims to assess changes in fixation eye movement and macular sensitivity following patching treatment and foveation therapy over a 12-week period. The study will enroll children aged 4-16 with specific types of amblyopia, utilizing interventions such as eye patches and foveation therapy to evaluate their effectiveness. The outcomes will help to better understand how these treatments impact visual function in affected children.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines,
2. ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic.

   * Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D;
   * strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery;
   * combined type included those who meet the criteria of both anisometropia and strabismus.
   * For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old.
   * For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old.

Exclusion Criteria:

* born before 32 weeks gestational age;
* neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies;
* congenital or acquired macular pathology.

Where it's running

• SUNY College of Optometry
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Jingyun Wang — SUNY College of Optmetry
• Study coordinator: Jingyun Wang, PhD
• Email: jwang@sunyopt.edu
• Phone: 2129385759

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• tDCS for paediatric amblyopia

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• Gamified visual training with occlusion for kids with anisometropic amblyopia

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.