Exploring treatments for amblyopia in children using OCT technology
OCT Eccentric Fixation, Fixation Stability, and Amblyopia in Children
This study is testing different treatments for amblyopia in children aged 4-16 to see how well they improve vision using eye patches and foveation therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 4 Years to 16 Years |
| Sex | All |
| Sponsor | State University of New York College of Optometry Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT05714449 on ClinicalTrials.gov |
What this trial studies
This study investigates the relationship between OCT eccentric fixation and various treatment methods for amblyopia in children. It aims to assess changes in fixation eye movement and macular sensitivity following patching treatment and foveation therapy over a 12-week period. The study will enroll children aged 4-16 with specific types of amblyopia, utilizing interventions such as eye patches and foveation therapy to evaluate their effectiveness. The outcomes will help to better understand how these treatments impact visual function in affected children.
Who should consider this trial
Good fit: Ideal candidates are children aged 4-16 with amblyopia characterized by specific visual acuity and ocular conditions.
Not a fit: Patients with amblyopia not meeting the inclusion criteria or those with other ocular conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for amblyopia, enhancing visual outcomes in children.
How similar studies have performed: While there have been studies on amblyopia treatments, the specific use of OCT eccentric fixation in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines, 2. ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic. * Anisometropia included interocular difference of spherical equivalent \>=1D or interocular difference of astigmatism cylinder magnitude \>=1D; * strabismus included those with deviation \>=10PD or good alignment after prior strabismus surgery; * combined type included those who meet the criteria of both anisometropia and strabismus. * For the patching group, we will enroll 15 children with strabismic amblyopia who are prescribed patching treatment. Age: 4-12 years old. * For the foveation therapy group, we will enroll 15 children with strabismic amblyopia who are prescribed foveation therapies. Age: 8-16 years old. Exclusion Criteria: * born before 32 weeks gestational age; * neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies; * congenital or acquired macular pathology.
Where this trial is running
New York, New York
- SUNY College of Optometry — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Jingyun Wang — SUNY College of Optmetry
- Study coordinator: Jingyun Wang, PhD
- Email: jwang@sunyopt.edu
- Phone: 2129385759
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.