Exploring the links between childhood trauma, attachment, and chronic pain.

Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience: When Psychological Dimensions Interfere With the Hospital Management of Pain

Observational University of Lorraine · NCT06077097

This study looks at how childhood trauma and attachment styles might affect how adults experience and manage chronic pain.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Lorraine Academic / other
Locations1 site (Metz, Lorraine,)
Trial IDNCT06077097 on ClinicalTrials.gov

What this trial studies

This observational study investigates the connections between adverse childhood experiences (ACEs), attachment styles, and chronic pain perception in adults. It aims to develop a comprehensive framework that incorporates psychological and biological factors to understand how these elements influence pain management outcomes. Participants will provide biological samples and complete questionnaires to assess their experiences and pain-related resilience. The study seeks to highlight the importance of a biopsychosocial approach in chronic pain management programs.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 with chronic pain lasting at least six months who can participate in a pain management program.

Not a fit: Patients with a history of specialized chronic pain management or significant psychiatric issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective and personalized chronic pain management strategies that consider psychological factors.

How similar studies have performed: While the exploration of ACEs in relation to chronic pain is still emerging, similar studies have shown promising links between psychological factors and pain outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have a chronic pain syndrome persisting for at least six months
* Have been referred to a chronic pain management programme at the Centre of evaluation and treatment of chronic pain at the "Belle- Isle" hospital (private hospital in Metz, France) or at the Pain Consultation of the Regional University Hospital of Nancy, France
* Be between 18 and 65 years old
* Be able to read and write in French (be able to understand the information and fill in the questionnaires independently)
* Agree to participate in the project and sign the consent form

Exclusion Criteria:

* Have received pain management in a specialised chronic pain facility (of any kind) during their lifetime
* Have physical, cognitive and/or linguistic deficiencies that make it impossible to fill in the questionnaires
* Have a psychiatric history (psychosis type)
* Have a drug or alcohol dependency
* Be a protected adult, under guardianship or curatorship
* Being pregnant or breastfeeding

Where this trial is running

Metz, Lorraine,

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainAdverse Childhood ExperiencesAttachment StylesChronic StressResilience, PsychologicalQuality of LifeEpigenesis, Genetic
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.