Exploring the link between unstable angina and anxiety-depressive syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between unstable angina pectoris and anxiety-depressive syndrome in patients with coronary artery disease. It includes 202 participants, with a focus on cytokine levels and uric acid in blood samples collected after fasting. The study employs established diagnostic criteria and scales to assess both physical and mental health aspects. The methodology involves detailed blood analysis using enzyme-linked immunosorbent assay (ELISA) to measure specific cytokines and uric acid levels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* the presence of an established diagnosis in patients with coronary artery disease
* unstable angina pectoris (NS). When making a diagnosis, the recommendations of ESH / ESC (2015) and RCO / WHO (2014) were used.
* stable exertional angina (SSN) I-III FC. When making the diagnosis, the IHD classification was used, adopted at the IV Congress of Cardiologists of the Republic of Uzbekistan (2000), as well as in accordance with the recommendations of ESH / ESC (2019) and RCO / WHO (2017)

Exclusion Criteria:

* The patient's refusal to participate in the study;
* Pregnancy and lactation;
* Severe and unstable condition of the patient, making it difficult to conduct a questionnaire (for ethical reasons);
* Acute violation of cerebral circulation;
* History of acute or chronic psychosis;
* The presence of concomitant acute diseases or chronic diseases in the acute stage.

Throughout the study, all patients were assigned the right to voluntarily withdraw from the study at their own request, notifying the researcher in writing or orally.

Where it's running

• Zarina
  Samarkand, Uzbekistan Recruiting

Study contacts

• Study coordinator: Zarina Nasirova, PhD
• Email: zarina.nasirova.91@mail.ru
• Phone: +998902768950

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.