Exploring the link between gut bacteria and stroke in young adults
Research on Correlation Between Intestinal Microecology Imbalance and the Risk and Prognosis of Stroke in Young Adults
This study looks at how gut bacteria might be linked to strokes in young adults aged 18-45 to see if it can help identify those at higher risk.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Shanghai 6th People's Hospital Academic / other |
| Locations | 2 sites (Shanghai and 1 other locations) |
| Trial ID | NCT05113043 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between intestinal microecology imbalance and stroke in young adults aged 18-45. By employing multi-omics technologies such as microbial diversity analysis, metagenomics, and metabonomics, the study aims to identify biomarkers that can predict outcomes after stroke and detect young individuals at high risk. The research focuses on understanding how gut health may influence the development and prognosis of ischemic and hemorrhagic strokes, particularly in the context of rising incidence rates among younger populations.
Who should consider this trial
Good fit: Ideal candidates for this study are young adults aged 18-45 who have been clinically diagnosed with acute ischemic or hemorrhagic stroke and admitted within 12 hours.
Not a fit: Patients with a history of neurological diseases, serious life-threatening conditions, or recent treatment with antibiotics, probiotics, or prebiotics may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new preventive strategies and treatments for stroke in young adults by targeting gut health.
How similar studies have performed: While the exploration of gut-brain interactions is a growing field, this specific approach using multi-omics in young stroke patients is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of acute ischemic or hemorrhagic stroke * Admission within 12 hours * Aged 18-45 years Exclusion Criteria: * History of neurological diseases, myocardial infarction, renal and hepatic abnormalities and metabolic diseases * Combined with tumors, inflammatory bowel disease and other digestive system diseases * Combined with serious life-threatening diseases or condition * Any antibiotics, probiotics or prebiotic treatment within 3 months * Deteriorate and die before collecting faecal samples
Where this trial is running
Shanghai and 1 other locations
- Shanghai 6th People's Hospital — Shanghai, China (Not_yet_recruiting)
- Shanghai 6th People's Hospital — Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Hao Chen, M.D., Ph.D.
- Email: chenhao_316@aliyun.com
- Phone: 02164369181
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.