Exploring the link between gut bacteria and stroke in young adults
Official title: Research on Correlation Between Intestinal Microecology Imbalance and the Risk and Prognosis of Stroke in Young Adults
Run by Shanghai 6th People's Hospital · NCT05113043 · Data updated 2026-11-12
This study looks at how gut bacteria might be linked to strokes in young adults aged 18-45 to see if it can help identify those at higher risk.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Shanghai 6th People's Hospital Academic / other |
| Locations | 2 sites (Shanghai and 1 other locations) |
| Status | Recruiting |
| Started | February 1, 2022 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | April 23, 2026 |
| Trial ID | NCT05113043 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are young adults aged 18-45 who have been clinically diagnosed with acute ischemic or hemorrhagic stroke and admitted within 12 hours.
✕Probably not a fit
Patients with a history of neurological diseases, serious life-threatening conditions, or recent treatment with antibiotics, probiotics, or prebiotics may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the relationship between intestinal microecology imbalance and stroke in young adults aged 18-45. By employing multi-omics technologies such as microbial diversity analysis, metagenomics, and metabonomics, the study aims to identify biomarkers that can predict outcomes after stroke and detect young individuals at high risk. The research focuses on understanding how gut health may influence the development and prognosis of ischemic and hemorrhagic strokes, particularly in the context of rising incidence rates among younger populations.
Why it matters
Potential benefit: If successful, this study could lead to new preventive strategies and treatments for stroke in young adults by targeting gut health.
How similar studies have gone: While the exploration of gut-brain interactions is a growing field, this specific approach using multi-omics in young stroke patients is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of acute ischemic or hemorrhagic stroke * Admission within 12 hours * Aged 18-45 years Exclusion Criteria: * History of neurological diseases, myocardial infarction, renal and hepatic abnormalities and metabolic diseases * Combined with tumors, inflammatory bowel disease and other digestive system diseases * Combined with serious life-threatening diseases or condition * Any antibiotics, probiotics or prebiotic treatment within 3 months * Deteriorate and die before collecting faecal samples
Where it's running
-
Shanghai 6th People's Hospital
Shanghai, China Recruiting -
Shanghai 6th People's Hospital
Shanghai, China Not yet recruiting
Study contacts
- Study coordinator: Hao Chen, M.D., Ph.D.
- Email: chenhao_316@aliyun.com
- Phone: 02164369181
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.