Exploring the link between antibodies and mental health in lupus patients
(Anti-Ribosomal P Protein,Anti-U1 RNP, Anti-Nucleosome and Anti-Double Strad DNA Antibodies) Correlate With Depression and Anxiety in Systemic Lupus Erythematosus Patients
This study is trying to see if certain antibodies in lupus patients are linked to feelings of depression and anxiety.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06255743 on ClinicalTrials.gov |
What this trial studies
This study investigates the relationship between specific antibodies and the levels of depression and anxiety in patients with Systemic Lupus Erythematosus (SLE). Using the Zung Self-Rating Depression Scale and the Zung Self-Rating Anxiety Scale, researchers will assess the mental health status of participants while measuring the presence of Anti-Ribosomal P Protein, Anti-U1 RNP, Anti-Nucleosome, and Anti-Double Stranded DNA antibodies. The goal is to better understand how these antibodies correlate with mental health issues in SLE patients.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with Systemic Lupus Erythematosus who meet specific classification criteria.
Not a fit: Patients with autoimmune diseases other than Systemic Lupus Erythematosus may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved mental health management strategies for patients with Systemic Lupus Erythematosus.
How similar studies have performed: While the specific approach of this study may be novel, there is existing literature exploring the relationship between autoimmune diseases and mental health.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients who fulfill the 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria or 2019 American College of Rheumatology/European League against Rheumatism classification criteria of Systemic Lupus Erythematosus. 2. Patients who is able to give informed consent to join the study. Exclusion Criteria: * - Any patient with any autoimmune disease other than systemic lupus erythematosus.
Where this trial is running
Sohag
- Sohag Faculty of Medicine — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Osama S Daif Allah, Assistant Professor
- Email: hebamaher1919@gmail.com
- Phone: 01006425746
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.