Exploring the impact of cognitive leisure activities on early Alzheimer's disease
Official title: The Impact of Cognitive Leisure Activity Levels on Cognitive Function in the Preclinical Stage of Alzheimer's Disease and the Study of Its Neural Circuitry Regulation Mechanisms
Run by Fujian Provincial Hospital · NCT06215274 · Data updated 2026-11-12
This study looks at how engaging in fun brain activities might help people with early signs of Alzheimer's disease think better and stay mentally active.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 156 (estimated) |
| Sponsor | Fujian Provincial Hospital Academic / other |
| Locations | 1 site (Fuzhou, Fujian) |
| Status | Recruiting |
| Started | April 27, 2024 |
| Main results expected | June 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | May 17, 2024 |
| Trial ID | NCT06215274 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 60 and older diagnosed with Mild Cognitive Impairment (MCI) or Subjective Cognitive Decline (SCD).
✕Probably not a fit
Patients with severe hearing or language impairments, or those with conditions that prevent them from undergoing MRI examinations, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and assess its reliability and validity. It will investigate the relationship between cognitive leisure activities and cognitive function in individuals at the preclinical stage of Alzheimer's Disease (AD). Additionally, the study seeks to clarify how cognitive leisure activities influence neural circuits in patients with Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD). By understanding these connections, the research hopes to inform early intervention strategies for AD.
Why it matters
Potential benefit: If successful, this study could lead to targeted interventions that delay or prevent the onset of Alzheimer's disease.
How similar studies have gone: While the specific approach of this study is novel, previous research has indicated that cognitive leisure activities can positively influence cognitive function in various populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD) * Age ≥ 60 years * Capable of normal communication in Mandarin,possesses a certain level of comprehension and judgment. Exclusion Criteria: * Individuals with severe hearing or language impairments, or with severe physical illnesses that are unable to cooperate with the survey * Individuals with pacemakers, metallic implants, cochlear implants, claustrophobia, and other contraindications for MRI examination.
Where it's running
-
Fujian Provincial Hospital
Fuzhou, Fujian, China Recruiting
Study contacts
- Study coordinator: Fayang Lian, MD
- Email: fjslkyk@163.com
- Phone: 0591-87557768
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.