Exploring the genetic factors in heart muscle disease related to pacemakers
Genetic Basis of Pacing-Induced Cardiomyopathy
This study is trying to find out if certain genes play a role in heart muscle disease for people who have pacemakers by collecting and analyzing their saliva samples.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 170 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The Guthrie Clinic Academic / other |
| Locations | 1 site (Sayre, Pennsylvania) |
| Trial ID | NCT03317964 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect saliva samples from patients who have pacemakers to investigate the genetic factors associated with cardiomyopathy, a condition characterized by abnormal heart muscle. The study will extract DNA from the saliva samples to analyze genetic variations that may contribute to the development of this condition. By understanding these genetic changes, researchers hope to gain insights into the mechanisms of pacing-induced cardiomyopathy. The study focuses on patients who have been evaluated for cardiomyopathy to ensure relevant data collection.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have been assessed for cardiomyopathy and have a pacemaker.
Not a fit: Patients without adequate follow-up care to determine their cardiomyopathy status may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cardiomyopathy in patients with pacemakers.
How similar studies have performed: While this study explores genetic factors in a specific context, similar genetic investigations in cardiomyopathy have shown promise in understanding the disease.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who have been assessed for cardiomyopathy Exclusion Criteria: * Patients who do not have adequate follow up care to determine if they do or do not have cardiomyopathy
Where this trial is running
Sayre, Pennsylvania
- Robert Packer Hospital — Sayre, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Pramod Deshmukh, MD — The Guthrie Clinic
- Study coordinator: Kamie Hoey, RN
- Email: Kamie.Hoey@guthrie.org
- Phone: 570-887-6070
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.