Exploring the effects of ZhenQiFuZheng granules on allergic rhinitis
Official title: Study on the Mechanism of ZhenQiFuZheng in the Treatment of Allergic Rhinitis Based on Intestinal Flora and Metabolites
Run by The First Affiliated Hospital with Nanjing Medical University · NCT06427577 · Data updated 2026-11-12
This study is testing if ZhenQi FuZheng granules can help people with allergic rhinitis by looking at how they affect gut bacteria and inflammation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | The First Affiliated Hospital with Nanjing Medical University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Nanjing, Jiangsu) |
| Status | Recruiting |
| Started | June 1, 2024 |
| Main results expected | June 1, 2025 |
| Study ends | June 1, 2028 |
| Registry record updated | December 9, 2024 |
| Trial ID | NCT06427577 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18-65 diagnosed with allergic rhinitis who are visiting the Department of Otolaryngology at the First Affiliated Hospital of Nanjing Medical University.
✕Probably not a fit
Patients with nasal diseases other than allergic rhinitis or those who refuse specimen and questionnaire collection may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the therapeutic effects of ZhenQi FuZheng granules on allergic rhinitis by examining its impact on intestinal flora and metabolites. It aims to establish a specimen library and utilize cell and animal models alongside clinical cohort research to assess the granules' mechanism of action. The hypothesis is that these granules can alter metabolic omics related to nasal inflammatory factors, potentially reducing type 2 inflammation in patients with allergic rhinitis.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the management of allergic rhinitis and enhance patients' quality of life.
How similar studies have gone: While the specific approach of using ZhenQi FuZheng granules in this context may be novel, similar studies exploring the relationship between traditional medicine and allergic conditions have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (18-65 years). * Patients who visited the Department of Otolaryngology of the First Affiliated Hospital of Nanjing Medical University and are diagnosed as allergic rhinitis . Exclusion Criteria: * Patients who refused to accept specimen and questionnaire collection. * Patients who had nasal diseases other than allergic rhinitis, such as nasal papilloma and nasal malignant tumor.
Where it's running
-
The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, China Recruiting
Study contacts
- Study coordinator: Lei Cheng
- Email: chenglei@jsph.org.cn
- Phone: +8613776620807
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.