Exploring the effects of walking with breath-holding on pain sensitivity

Effects of Walking Apnea At High Lung Volume on Hypoalgesia

NA · Universidad Rey Juan Carlos · NCT06638528

This study tests if walking while holding your breath can help healthy people feel less pain compared to normal breathing.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversidad Rey Juan Carlos (other)
Locations1 site (Madrid)
Trial IDNCT06638528 on ClinicalTrials.gov

What this trial studies

This study investigates how a 6-minute session of intermittent walking while holding one's breath at high lung volume affects pain sensitivity in healthy individuals. It aims to determine the hypoalgesic response, which is the reduction in pain perception, during this unique breathing exercise. Additionally, the study will assess the cardiovascular and respiratory responses elicited by the intervention. Participants will be randomly assigned to either the walking apnea or normal breathing group to compare outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy individuals aged 18 to 64 who do not have any underlying health conditions.

Not a fit: Patients with cardiovascular, respiratory, metabolic, neurological, or osteomuscular conditions, as well as those experiencing pain on the day of the study, will not benefit from this intervention.

Why it matters

Potential benefit: If successful, this approach could provide new insights into non-pharmacological methods for pain management.

How similar studies have performed: While the specific approach of walking apnea at high lung volume is novel, similar studies exploring breathing techniques and pain modulation have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Asymptomatic subjects aged between 18 and 64 years.

Exclusion Criteria:

* Cardiovascular, respiratory, metabolic, neurological or osteomuscular signs or pathologies.

  * History of epilepsy.
  * Pregnant
  * Pharmacological treatment.
  * Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 4 weeks.

Where this trial is running

Madrid

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pain, Hypoxemia, Hypercapnia, Apnea

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.