Exploring taste problems linked to dry mouth in advanced cancer patients
An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer
This study looks at how dry mouth affects taste and overall well-being in people with advanced cancer to see how these issues impact their quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Our Lady's Hospice and Care Services Academic / other |
| Locations | 1 site (Dublin) |
| Trial ID | NCT06287294 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between xerostomia (dry mouth) and taste disturbances in patients with advanced cancer. It aims to understand how these symptoms affect the quality of life, dietary intake, and emotional well-being of patients. By assessing the severity of both dry mouth and taste problems, the study seeks to provide insights into the prevalence and impact of these conditions in this population. The findings could help inform better management strategies for patients experiencing these distressing symptoms.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with locally advanced or metastatic cancer who experience moderate or worse dry mouth and taste problems.
Not a fit: Patients with cognitive impairments, those whose dry mouth or taste problems preceded their cancer diagnosis, or those in the terminal phase of illness may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of taste and dry mouth issues, enhancing the quality of life for patients with advanced cancer.
How similar studies have performed: While there is limited data on this specific relationship, previous studies have identified associations between xerostomia and taste disturbances, suggesting potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age * Diagnosis of locally advanced or metastatic cancer * Referred to palliative care/oncology services * Dry mouth rated 'moderate' or worse over previous 2-week period * Taste problems rated 'moderate' or worse over previous 2-week period * Good understanding of English Exclusion Criteria: * Cognitive impairment (unable to provide consent / complete questionnaire) * Dry mouth precedes cancer diagnosis. * Taste problems precedes cancer diagnosis. * Head and neck surgery * Head and neck radiotherapy * Salivary gland disorders (e.g., Sjogren's Syndrome) * In the 'Deteriorating' or 'Terminal' Phase of illness
Where this trial is running
Dublin
- Our Lady's Hospice and Care Services — Dublin, Ireland (Recruiting)
Study contacts
- Principal investigator: Andrew Davies, FRCP — Our Lady's Hospice and Care Services
- Study coordinator: Andrew Davies, FRCP
- Email: andavies@tcd.ie
- Phone: 0035314986235
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.