Exploring sleep patterns and apnea in individuals with Down syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize sleep disorders, particularly sleep apnea, in individuals with Down syndrome. It focuses on identifying the determinants and consequences of these sleep disorders, which are common in this population. By phenotyping sleep characteristics, the study seeks to facilitate early diagnosis and intervention, ultimately improving health outcomes for affected individuals. The research will involve assessing various risk factors associated with sleep disorders in children with Down syndrome.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Total autosomal trisomy caused by the presence of a third copy (partial or total) of chromosome 21

Exclusion Criteria:

* People with abnormal electrocardiographic tracings,
* Existence of heart failure or cardiovascular disease, as determined by any abnormalities in cardiovascular adaptations to exercise.
* Existence of a declared or uncontrolled progressive disease.
* pregnant or breast-feeding women.

Where it's running

• Chu Grenoble Alpes
  La Tronche, France Recruiting

Study contacts

• Principal investigator: Sébastien BAILLIEUL — University Grenoble Hospital
• Study coordinator: Veronique BRICOUT
• Email: VBricout@chu-grenoble.fr
• Phone: 0476767226

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• JAK inhibitor treatment for Down syndrome in children and young adults

  This study tests whether 6 months of tofacitinib can help improve safety and neurodevelopment in people with Down syndrome aged 6 to 22, compared with placebo.

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• Jump rope to improve navicular drop and foot posture in children with Down syndrome

  This project will test whether adding jump-rope exercises to play activities helps improve foot posture in 4–15-year-old children with Down syndrome who have navicular drop.

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• Thymus removal and immune aging in people with Down syndrome

  This study will try to see if removing part of the thymus affects immune health over time in people aged 1 and older with Down syndrome, comparing those who had thymectomy to those who did not and to unaffected household relatives.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07416201

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.