Exploring sleep patterns and apnea in individuals with Down syndrome
Down Syndrome, Physical Activity and Sleep Apnea
This study is trying to understand sleep problems, especially sleep apnea, in children with Down syndrome to help find ways to diagnose and treat these issues early.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | University Hospital, Grenoble Academic / other |
| Locations | 1 site (La Tronche) |
| Trial ID | NCT06061562 on ClinicalTrials.gov |
What this trial studies
This observational study aims to characterize sleep disorders, particularly sleep apnea, in individuals with Down syndrome. It focuses on identifying the determinants and consequences of these sleep disorders, which are common in this population. By phenotyping sleep characteristics, the study seeks to facilitate early diagnosis and intervention, ultimately improving health outcomes for affected individuals. The research will involve assessing various risk factors associated with sleep disorders in children with Down syndrome.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with Down syndrome, specifically those exhibiting symptoms of sleep disorders.
Not a fit: Patients with significant cardiovascular issues or uncontrolled progressive diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier diagnosis and better management of sleep disorders in individuals with Down syndrome, improving their overall health and quality of life.
How similar studies have performed: While sleep disorders in Down syndrome have been previously studied, this specific phenotyping approach focusing on sleep apnea is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Total autosomal trisomy caused by the presence of a third copy (partial or total) of chromosome 21 Exclusion Criteria: * People with abnormal electrocardiographic tracings, * Existence of heart failure or cardiovascular disease, as determined by any abnormalities in cardiovascular adaptations to exercise. * Existence of a declared or uncontrolled progressive disease. * pregnant or breast-feeding women.
Where this trial is running
La Tronche
- Chu Grenoble Alpes — La Tronche, France (Recruiting)
Study contacts
- Principal investigator: Sébastien BAILLIEUL — University Grenoble Hospital
- Study coordinator: Veronique BRICOUT
- Email: VBricout@chu-grenoble.fr
- Phone: 0476767226
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.