Exploring sexual dysfunction in women with high blood pressure

Sexual Dysfunction in Hypertensive Women According to Drug Adherence: Multicenter Cross-sectional Study

NA · University Hospital, Toulouse · NCT05156385

This study is trying to see how high blood pressure and its treatments affect sexual health in women to help improve their overall well-being and treatment adherence.

Quick facts

PhaseNA
Study typeInterventional
Enrollment348 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity Hospital, Toulouse (other)
Locations1 site (Toulouse, CHU de Toulouse)
Trial IDNCT05156385 on ClinicalTrials.gov

What this trial studies

This study investigates the relationship between sexual dysfunction and hypertension in women, focusing on those treated with various antihypertensive medications. It aims to assess the prevalence of sexual dysfunction and the factors contributing to medication non-adherence through questionnaires and blood samples. The study will analyze the impact of antihypertensive drugs on sexual activity and the psychological aspects related to anxiety and depression. By understanding these dynamics, the research seeks to improve treatment adherence and overall patient well-being.

Who should consider this trial

Good fit: Ideal candidates include women over 18 with confirmed hypertension who are being treated with specific antihypertensive medications.

Not a fit: Patients with a history of bariatric surgery, those under legal guardianship, or those diagnosed with severe mental health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management of sexual dysfunction in hypertensive women, enhancing their quality of life.

How similar studies have performed: While there have been studies exploring sexual dysfunction in hypertensive patients, this specific approach focusing on medication adherence and psychological factors is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women over 18,
* Hospitalized or received in consultation for the management of hypertension treated in one of the hypertension and therapeutic, nephrology or cardiology departments participating in the study, with confirmed hypertension, treated with the following dosable antihypertensive agent(s): diltiazem, verapamil, acebutolol, atenolol, nébivolol, bisoprolol, metoprolol, propranolol, amiloride, furosemide, hydrochlorothiazide, indapamide, spironolactone, spironolactone, Lorsartan, Irbesartan, Ramipril, Perindopril, Amlodipine,
* Having signed the informed consent form.
* Beneficiary or affiliated to a French Social insurance

Exclusion Criteria:

* Patients with bariatric surgery,
* Patients under guardianship/trusteeship/protection of justice,
* Patients with diagnosed and treated psychosis or depression, - Pregnant or nursing women.

Where this trial is running

Toulouse, CHU de Toulouse

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Hypertension, high blood pressure, antihypertensive drugs, sexual dysfunction

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.