Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Exploring how muscle pain affects walking mechanics

Official title: Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity

Run by Aalborg University · NCT06411197 · Data updated 2026-11-12

This study tests how causing muscle pain affects the way healthy people walk and use their muscles.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment36 (estimated)
SponsorAalborg University
Academic / other
Locations1 site (Aalborg, North Denmark)
StatusRecruiting
StartedNovember 8, 2023
Main results expectedJune 1, 2026
Study endsDecember 31, 2026
Registry record updatedOctober 2, 2025
Trial IDNCT06411197 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy men and women aged 18-45 years without any current pain or musculoskeletal issues.

Probably not a fit

Patients with existing pain, neurological disorders, or those who are pregnant will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates the impact of induced muscle pain on gait biomechanics in healthy individuals. Participants will receive injections of hypertonic saline to create a painful condition and isotonic saline as a control, targeting specific muscles in the lower extremities. The study employs a randomized, crossover design where participants will undergo motion capture and electromyography assessments while walking after each injection. The goal is to understand how pain influences movement patterns and muscle activation.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of musculoskeletal pain and improve treatment strategies for pain management.

How similar studies have gone: While studies on biomechanics and pain exist, this specific approach using hypertonic saline injections in a crossover design is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy men and women aged 18-45 years

Exclusion Criteria:

* Pregnancy
* Drug addiction, defined as the use of cannabis, opioids, or other drugs
* Previous or current neurologic or musculoskeletal illnesses
* Current pain
* Lack of ability to cooperate

Where it's running

  • Aalborg University
    Aalborg, North Denmark, Denmark
    Recruiting

Study contacts

  • Principal investigator: Kristian KS Petersen — Aalborg University
  • Study coordinator: Kristian KS Petersen
  • Email: kkp@hst.aau.dk
  • Phone: 31697510

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.