Exploring how muscle pain affects walking mechanics
Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
This study tests how causing muscle pain affects the way healthy people walk and use their muscles.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 36 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Aalborg University Academic / other |
| Locations | 1 site (Aalborg, North Denmark) |
| Trial ID | NCT06411197 on ClinicalTrials.gov |
What this trial studies
This interventional study investigates the impact of induced muscle pain on gait biomechanics in healthy individuals. Participants will receive injections of hypertonic saline to create a painful condition and isotonic saline as a control, targeting specific muscles in the lower extremities. The study employs a randomized, crossover design where participants will undergo motion capture and electromyography assessments while walking after each injection. The goal is to understand how pain influences movement patterns and muscle activation.
Who should consider this trial
Good fit: Ideal candidates are healthy men and women aged 18-45 years without any current pain or musculoskeletal issues.
Not a fit: Patients with existing pain, neurological disorders, or those who are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of musculoskeletal pain and improve treatment strategies for pain management.
How similar studies have performed: While studies on biomechanics and pain exist, this specific approach using hypertonic saline injections in a crossover design is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy men and women aged 18-45 years Exclusion Criteria: * Pregnancy * Drug addiction, defined as the use of cannabis, opioids, or other drugs * Previous or current neurologic or musculoskeletal illnesses * Current pain * Lack of ability to cooperate
Where this trial is running
Aalborg, North Denmark
- Aalborg University — Aalborg, North Denmark, Denmark (Recruiting)
Study contacts
- Principal investigator: Kristian KS Petersen — Aalborg University
- Study coordinator: Kristian KS Petersen
- Email: kkp@hst.aau.dk
- Phone: 31697510
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.