Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Exploring how coffee affects energy use and caffeine processing

Official title: The Effect of Coffee on Energy Expenditure and Caffeine Metabolism

Run by Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences · NCT06712511 · Data updated 2026-11-12

This study tests how drinking coffee affects energy use and how the body processes caffeine in healthy people.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment60 (estimated)
SponsorShenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Academic / other
Locations1 site (Shenzhen, Guangdong)
StatusRecruiting
StartedOctober 23, 2024
Main results expectedJune 30, 2029
Study endsDecember 31, 2029
Registry record updatedMarch 27, 2025
Trial IDNCT06712511 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy adults who regularly consume coffee.

Probably not a fit

Patients with conditions such as diabetes, hypertension, or other specified health issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates the relationship between coffee consumption and energy expenditure, as well as how the body metabolizes caffeine. Healthy participants will be recruited and required to abstain from stimulant drinks for 24 hours prior to the experiment. During the study, various physiological parameters such as total energy expenditure, heart rate, and cognitive function will be monitored. Blood and urine samples will be analyzed to measure caffeine levels and its metabolites using advanced chromatography techniques.

Why it matters

Potential benefit: If successful, this study could provide insights into how coffee consumption can enhance energy expenditure, potentially aiding in obesity prevention and treatment.

How similar studies have gone: While there have been studies on caffeine and metabolism, this specific investigation into coffee's effects on energy expenditure is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy adults.
* Must be able to drink coffee.

Exclusion Criteria:

* Diabetes.
* Hypoglycemia.
* Gout.
* Osteoporosis.
* Gastric ulcer.
* Pancreatitis.
* Intestinal obstruction.
* Blood phobia.
* Pathological hypo or hyper tension.
* Impaired glucose tolerance.
* Claustrophobia.
* HIV,etc.

Where it's running

  • Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
    Shenzhen, Guangdong, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.