Exploring how brain development affects social emotions and communication in young children
Official title: A Cohort Study on the Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years
Run by Children's Hospital of Fudan University · NCT05040542 · Data updated 2026-11-12
This study looks at how the development of a child's brain affects their ability to express emotions and communicate as they grow from infants to young children.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 6 Years |
| Sex | All |
| Enrollment | 3001 (estimated) |
| Sponsor | Children's Hospital of Fudan University Academic / other |
| Locations | 1 site (Xiamen, Fujian) |
| Status | Recruiting |
| Started | August 1, 2021 |
| Main results expected | August 31, 2026 |
| Study ends | August 31, 2026 |
| Registry record updated | November 19, 2024 |
| Trial ID | NCT05040542 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are infants aged 0 to 6 years who were born between 34-42 weeks of gestation and have a birth weight greater than 1500g.
✕Probably not a fit
Patients who may not benefit from this study include those with severe complications during pregnancy, congenital malformations, or contraindications to MRI scanning.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the connection between brain development and the social emotion and communication abilities of infants aged 0 to 6 years. Utilizing advanced functional magnetic resonance imaging (fMRI) techniques, the study aims to analyze brain function and structure in response to various stimuli and conditions. Researchers will also assess genetic factors and maternal health during pregnancy to identify potential influences on brain development. The study employs various assessment scales to evaluate children's emotional and social behaviors alongside their brain imaging results.
Why it matters
Potential benefit: If successful, this study could lead to targeted interventions that improve social and emotional development in infants.
How similar studies have gone: Other studies have shown success in using fMRI to explore brain development in children, making this approach both relevant and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 0-6 years 2. Born at 34-42 weeks of gestation 3. Birth weight\>1500g 4. Normal brain function assessment 5. Parents can understand and sign informed consent Exclusion Criteria: 1. The mother had severe complications during pregnancy and delivery 2. History of asphyxiation at birth 3. Have congenital structural malformation 4. Have congenital metabolic disease 5. Have major or genetic diseases that affect growth, development or cognition 6. Have contraindications to MRI scanning
Where it's running
-
Xiamen Children's Hospital
Xiamen, Fujian, China Recruiting
Study contacts
- Study coordinator: Wenhao Zhou, Prof
- Email: zwhchfu@126.com
- Phone: (+86) 021-64931168
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Prenatal choline supplementation to support fetal brain development
This study tests whether giving pregnant people choline can help their babies' brain development and growth, compared with a placebo, when alcohol exposure is not present.
-
Interactive massage for toddlers with autism
A mom-led 3-month interactive massage program is being tested to see if it improves parent-child interaction in toddlers with autism, compared with usual care.
-
Parent-Mediated Social-Cognition Intervention for Young Children with Autism
This study tests a parent-led, home-based play program to help young children with autism improve social-cognition skills.
-
Early Nutrition Support for Extremely Preterm Infants
This initiative tests a nutrition bundle—personalized breast milk feeding, early zinc supplementation, and routine carnitine supplementation—for very preterm babies to see if it improves growth and development.
-
Atorvastatin in Chinese children with Kawasaki disease and coronary artery abnormalities
This phase 3 study tests whether atorvastatin is safe and helpful for children with Kawasaki disease who have coronary artery abnormalities.
-
Child Life Services to Help Kids During Skin Prick Testing
This study tests whether child life services can ease pain and anxiety for children and reduce caregiver stress during skin prick testing.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.