Exploring how brain development affects social emotions and communication in young children
A Cohort Study on the Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years
This study looks at how the development of a child's brain affects their ability to express emotions and communicate as they grow from infants to young children.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3001 (estimated) |
| Ages | N/A to 6 Years |
| Sex | All |
| Sponsor | Children's Hospital of Fudan University Academic / other |
| Locations | 1 site (Xiamen, Fujian) |
| Trial ID | NCT05040542 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the connection between brain development and the social emotion and communication abilities of infants aged 0 to 6 years. Utilizing advanced functional magnetic resonance imaging (fMRI) techniques, the study aims to analyze brain function and structure in response to various stimuli and conditions. Researchers will also assess genetic factors and maternal health during pregnancy to identify potential influences on brain development. The study employs various assessment scales to evaluate children's emotional and social behaviors alongside their brain imaging results.
Who should consider this trial
Good fit: Ideal candidates for this study are infants aged 0 to 6 years who were born between 34-42 weeks of gestation and have a birth weight greater than 1500g.
Not a fit: Patients who may not benefit from this study include those with severe complications during pregnancy, congenital malformations, or contraindications to MRI scanning.
Why it matters
Potential benefit: If successful, this study could lead to targeted interventions that improve social and emotional development in infants.
How similar studies have performed: Other studies have shown success in using fMRI to explore brain development in children, making this approach both relevant and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 0-6 years 2. Born at 34-42 weeks of gestation 3. Birth weight\>1500g 4. Normal brain function assessment 5. Parents can understand and sign informed consent Exclusion Criteria: 1. The mother had severe complications during pregnancy and delivery 2. History of asphyxiation at birth 3. Have congenital structural malformation 4. Have congenital metabolic disease 5. Have major or genetic diseases that affect growth, development or cognition 6. Have contraindications to MRI scanning
Where this trial is running
Xiamen, Fujian
- Xiamen Children's Hospital — Xiamen, Fujian, China (Recruiting)
Study contacts
- Study coordinator: Wenhao Zhou, Prof
- Email: zwhchfu@126.com
- Phone: (+86) 021-64931168
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.