Exploring how Alzheimer's affects response to brain stimulation therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of transcranial direct current stimulation (tDCS) on individuals with Alzheimer's Disease (AD) and Frontotemporal dementia (FTD). The researchers aim to determine the optimal stimulation parameters, specifically testing a higher intensity of 4.0 mA compared to the conventional 2.0 mA, to enhance therapeutic responses. By assessing cognitive improvements through tDCS combined with cognitive training, the study seeks to identify which patients may benefit most from this intervention. The variability in previous studies' results prompts this investigation to refine treatment approaches for better clinical outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Mild to Moderate AD
* Score between 18 and 25 on the MoCA
* Able to do the N-Back task during the initial screening

Exclusion Criteria:

* No history of stroke or TBI
* No shunts or metal in the body
* No history of significant heart disease, alcoholism and drug use

Where it's running

• Baycrest Health Sciences
  Toronto, Ontario, Canada Recruiting

Study contacts

• Study coordinator: Carlos Roncero, PhD
• Email: troncero@research.baycrest.org

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.