Exploring genetic causes of ALS in Norway
Genetisk Studie av Amyotrofisk Lateral Sklerose (ALS)
This study is trying to find out if certain genes are linked to ALS by asking people with the disease in Norway about their family history and taking a blood sample for testing.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 16 Years to 100 Years |
| Sex | All |
| Sponsor | Sykehuset Telemark Government |
| Locations | 17 sites (Bergen and 16 other locations) |
| Trial ID | NCT05119387 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the genetic factors associated with the development of Amyotrophic Lateral Sclerosis (ALS) in Norway. Participants diagnosed with probable or definite ALS will complete a questionnaire about their family history and provide a blood sample for genetic analysis. The collected data, including clinical information and consent forms, will be sent to the Department of Medical Genetics at Telemark Hospital Trust for analysis. Patients will have the option to receive their genetic results in a diagnostic context.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with probable or definite ALS who are able to provide informed consent.
Not a fit: Patients who are not competent to give consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the genetic underpinnings of ALS, potentially leading to improved diagnosis and treatment options for patients.
How similar studies have performed: Other studies exploring genetic factors in ALS have shown promise, indicating that this approach is supported by previous research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Probable or definite ALS * Eligible to consent Exclusion Criteria: \- not competent to give consent
Where this trial is running
Bergen and 16 other locations
- Haukeland University Hospital, Department of Neurology — Bergen, Norway (Recruiting)
- Nordland Hospital Trust, Department of Neurology — Bodø, Norway (Recruiting)
- Vestre Viken Hospital Trust, Department of Neurology — Drammen, Norway (Recruiting)
- Førde Hospital Trust, Department of Neurology — Førde, Norway (Recruiting)
- Østfold Hospital Trust, Department of Neurology — Grålum, Norway (Recruiting)
- Fonna Hospital Trust, Department of Neurology — Haugesund, Norway (Recruiting)
- Sørlandet Hospital Trust, Department of Neurology — Kristiansand, Norway (Recruiting)
- Innlandet Hospital Trust, Department of Neurology — Lillehammer, Norway (Recruiting)
- Akershus University Hospital, Department of Neurology — Lørenskog, Norway (Recruiting)
- Møre and Romsdal Hospital Trust, Department of Neurology — Molde, Norway (Recruiting)
- Nord-Trøndelag Hospital Trust, Department of Neurology — Namsos, Norway (Recruiting)
- Oslo University Hospital, Department of Neurology — Oslo, Norway (Recruiting)
- Telemark Hospital, Department of Neurology — Skien, Norway (Recruiting)
- Stavanger University Hospital, Department of Neurology — Stavanger, Norway (Recruiting)
- University hospital of North Norway, Department of Neurology — Tromsø, Norway (Recruiting)
- St. Olavs Hospital, Department of Neurology — Trondheim, Norway (Recruiting)
- Vestfold Hospital Trust, Department of Neurology — Tønsberg, Norway (Recruiting)
Study contacts
- Principal investigator: Helle Høyer — Telemark Hospital Trust, Norway
- Study coordinator: Helle Høyer
- Email: helle.hoyer@sthf.no
- Phone: 35003146
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.