Exploring Early Maladaptive Schemas in Stable Bipolar Disorder Patients

Early Maladaptative Schemas Among Euthymic Patients With Bipolar Disorder: Exploring the Relationships With Symptoms, Functioning and Cognition in the Versailles FondaMental Advanced Centers of Expertise for Bipolar Disorders

Observational Versailles Hospital · NCT03977909

This study looks at how certain negative thought patterns affect people with stable bipolar disorder to see if they relate to their mental health and daily functioning.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorVersailles Hospital Academic / other
Locations1 site (Le Chesnay)
Trial IDNCT03977909 on ClinicalTrials.gov

What this trial studies

This observational study investigates Early Maladaptive Schemas (EMS) in patients with euthymic bipolar disorder, aiming to identify different clusters of EMS and their relationship with clinical characteristics and neuropsychological performance. Data will be collected from the Versailles Expert Center for Bipolar Disorder over a period of 24 months, with assessments at baseline, 12 months, and 24 months. The study also seeks to quantify the impact of EMS on psychosocial functioning, taking into account cognitive factors and residual depressive symptoms.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with bipolar disorder who are currently in a stable, euthymic state.

Not a fit: Patients experiencing major depressive, manic, or hypomanic episodes during evaluation will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of how EMS affect functioning in bipolar disorder, potentially leading to improved therapeutic strategies.

How similar studies have performed: While few studies have focused on EMS in bipolar disorder, the approach of examining their impact on functioning is relatively novel and underexplored.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

- bipolar disorder according to DSM IV-R (structured clinical interview)

Exclusion Criteria:

* major depressive or manic or hypomanic during the evaluation
* Montgomery Åsberg Depression Rating Scale ⩽10
* Young Mania Rating Scale ⩽12

Where this trial is running

Le Chesnay

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bipolar DisorderEarly Maladaptative SchemasCognitionFunctioning
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.