Exploring cognitive and physical rehabilitation in brain tumor patients undergoing radiotherapy
Official title: Analysis of the Cognitive-behavioral Dysfunctions Profile and the Potential of Neuroplasticity in Patients With Brain Tumors Subjected to Selected Radiotherapy Techniques and the Possibility of Their Compensation by Psycho-physical Training
Run by The Greater Poland Cancer Centre · NCT05192447 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether exercise can help brain tumor patients improve their thinking and memory while they are undergoing radiotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | The Greater Poland Cancer Centre Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Poznań, Greater Poland) |
| Trial ID | NCT05192447 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18-70 with primary or metastatic brain tumors who are in good health and undergoing radiotherapy.
✕Probably not a fit
Patients with multiple tumors, significant neurological disorders, or severe circulatory failure may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the cognitive and behavioral dysfunctions experienced by brain tumor patients during radiotherapy, focusing on the potential for neuroplasticity and rehabilitation through exercise. It aims to analyze the impact of different radiation therapy techniques on cognitive function and identify molecular markers associated with brain changes. The study will quantitatively evaluate how exercise influences brain activity and cognitive performance in patients receiving treatment for brain tumors. By understanding these relationships, the researchers hope to develop effective strategies to mitigate cognitive impairments caused by radiation therapy.
Why it matters
Potential benefit: If successful, this study could lead to improved cognitive and physical rehabilitation strategies for brain tumor patients undergoing radiotherapy.
How similar studies have gone: While the specific approach of this study is novel, there is emerging evidence that exercise can positively influence cognitive function in cancer patients, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Patients with three different CNS groups of tumors: from III and IV brain tumor groups, and metastatic tumors enrolled to RT, * Age between 18-70 years, * good general health conditions (according to Eastern Cooperative Oncology Group (ECOG) 0-2), * obtaining informed consent for participation in the study. Exclusion criteria: * Patients with numerous tumors (above two), * psychological or psychiatric illnesses treated pharmacologically, * neurological disorders (e.g. MS, Parkinson's disease, meningitis, etc.), * significant clinical circulatory failure (above III NYHA).
Where it's running
-
Greater Poland Cancer Centre
Poznań, Greater Poland, Poland Recruiting
Study contacts
- Principal investigator: Katarzyna Hojan, MD, PhD — Greater Poland Cancer Centre
- Study coordinator: Katarzyna Hojan, MD, PhD
- Email: katarzyna.hojan@wco.pl
- Phone: +48601509967
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.