Exploring brain health using non-invasive imaging techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study investigates neurophysiological markers of brain health by utilizing a combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG). Participants, who are already involved in a related study, will undergo two in-person sessions with the Delphi-MD device to assess brain responses to magnetic stimulation. The study aims to correlate these neurophysiological metrics with behavioral and fMRI data collected from the participants. This innovative approach seeks to enhance our understanding of brain health through non-invasive imaging.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Must be an active brain imaging participant in The BrainHealth Project (NCT04869111)
* Minimum age of 22
* Fluent in English
* Able to read \& hear information over a computer
* Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center.
* Must pass a modified TMS Adult Safety Screen
* Meet all criteria for study as determined by the study physician

Exclusion Criteria:

* A diagnosis of a neurodegenerative disease
* A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level
* A diagnosis of autism spectrum disorder that currently hinders them from functioning independently.
* Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants)
* Magnetically activated implants or electronically implanted devices
* Medication pumps
* Personal or family history of epilepsy, seizure(s), seizure disorder.
* History of, or risk factors for syncope (fainting)
* Report significant cognitive challenges
* Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism)
* Have claustrophobia

Where it's running

• Center for BrainHealth at The University of Texas at Dallas
  Dallas, Texas, United States Recruiting

Study contacts

• Principal investigator: Sandra Chapman, PhD — The University of Texas at Dallas
• Study coordinator: Erin Venza, MS
• Email: erin.venza@utdallas.edu
• Phone: 972-883-3208

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.