Exploring blood markers related to delirium after heart surgery
Exploring of Serum Biomarkers of Delirium After Cardiovascular Surgery
Huazhong University of Science and Technology · NCT06007755
This study is trying to see if certain blood markers can help predict or explain delirium in patients after heart surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 113 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Huazhong University of Science and Technology (other) |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT06007755 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between serum biomarkers and the occurrence of delirium in patients following cardiovascular surgery. It focuses on the role of histone lactylation and Alzheimer's disease-related markers in understanding the mechanisms behind postoperative delirium. By analyzing serum samples, the study aims to identify potential biomarkers that could predict or explain delirium in this patient population. The findings could enhance our understanding of delirium and its inflammatory connections in the context of cardiovascular procedures.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled to undergo cardiovascular surgery who can provide informed consent.
Not a fit: Patients with a history of neurological or psychiatric diseases, or severe sensory impairments, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved identification and management of delirium in patients after cardiovascular surgery.
How similar studies have performed: While the specific approach of this study is novel, previous research has indicated a connection between biomarkers and delirium, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: patients who receive cardiovascular surgery * Patients participated voluntarily and signed informed consent Exclusion Criteria: * past medical history of neurological and psychiatric diseases; severe visual or hearing impairment;
Where this trial is running
Wuhan, Hubei
- Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China (RECRUITING)
Study contacts
- Study coordinator: Hua Zheng, Dr.
- Email: hzheng@hust.edu.cn
- Phone: 0086-27-83663173
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Delirium, delirium, biomarker, cardiovascular surgery, H3K18la, exosome, phospho-tau, Aβ