Exploring anesthesia machine effects on bariatric surgery patients
Effects of Different Ventilation Modes on Intracranial Pressure and Carbon Dioxide Partial Pressure During Bariatric Surgery: a Prospective, Randomized, Controlled Study
This study tests how different breathing machines during bariatric surgery affect patients' breathing and pressure in the brain to see which method is best for them.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 16 Years to 65 Years |
| Sex | All |
| Sponsor | Inner Mongolia University of Science and Technology Academic / other |
| Locations | 1 site (Baotou, Inner Mongolia) |
| Trial ID | NCT06547411 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of different ventilation modes—PC, VC, and PRVC—on bariatric surgery patients. It aims to determine how these modes affect intracranial pressure and carbon dioxide levels during surgery. Participants will be randomized into groups receiving each ventilation mode, and their respiratory mechanics, partial pressure of carbon dioxide, and optic nerve sheath diameter will be monitored for comparison. The study seeks to provide insights into optimizing anesthesia for this patient population.
Who should consider this trial
Good fit: Ideal candidates are patients aged 16 to 65 scheduled for elective bariatric surgery with a BMI of 35 or higher.
Not a fit: Patients with severe mental disabilities, ocular conditions, or those dependent on alcohol or opioids may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved anesthesia management and outcomes for bariatric surgery patients.
How similar studies have performed: While the specific approach of comparing these ventilation modes in bariatric surgery is novel, similar studies have shown varying success in optimizing ventilation strategies in surgical settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for elective bariatric surgery. * Age between 16 and 65 years. * Continuous weight gain for more than 5 years with a BMI ≥ 35. * ASA-PS (American Society of Anesthesiologists Physical Status) categorization of Grade II or III. Exclusion Criteria: * Patients who were dependent on alcohol or opioids. * Patients with severe mental or intellectual disabilities. * Patients with severe ocular conditions, such as ocular trauma, optic nerve tumors, or those wearing ocular prostheses.
Where this trial is running
Baotou, Inner Mongolia
- Inner Mongolia Baogang Hospital — Baotou, Inner Mongolia, China (Recruiting)
Study contacts
- Study coordinator: Yu-Long Jia
- Email: jiayulong97@gmail.com
- Phone: 14747606821
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.