Expanding access to opioid addiction treatment in Central Asia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This initiative aims to address the growing HIV epidemic in Central Asia, particularly among people who inject drugs (PWID) and their partners, by scaling up opioid agonist therapies (OAT). The study employs the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to enhance OAT delivery in Kazakhstan, Kyrgyzstan, and Tajikistan. By utilizing the Exploration-Planning-Implementation-Sustainment (EPIS) framework, the project seeks to understand and improve the implementation of OAT in these regions, ultimately aiming to create communities of practice that can tackle healthcare delivery challenges. The study will involve quantitative surveys and focus groups with PWID and OAT delivery staff to gather insights and improve treatment access.

Why it matters

Who can join: the full rules

Inclusion Criteria:

i. Aim 1: The inclusion criteria for Aim 1 Consists of:

1. Quantitative surveys for PWID

   1. 18 years or older
   2. Meeting DSM-V criteria for opioid dependence
   3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
2. Organizational Assessments for OAT Delivery Staff

   1. 18 years or older
   2. Currently working as an OAT delivery professional at an OAT delivery site
3. Focus Groups (PWID on OAT)

   1. 18 years or older
   2. Meeting DSM-V criteria for opioid dependence
   3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
4. Focus Groups (PWID not on OAT)

   1. 18 years or older
   2. Meeting Diagnostic and Statistical Manual of Mental Disorders(DSM)-V criteria for opioid dependence
   3. Be OAT naïve (defined as never having been on OAT or having not received treatment for \> 1 year)
5. Focus Groups (OAT delivery staff)

   1. 18 years or older
   2. Currently working as an OAT delivery professional at an OAT delivery site

ii. Aim 2: The inclusion criteria for Aim 2 consists of:

1. 18 years or older
2. Currently assigned as a Chief Narcologist for an Oblast

iii. Aim 3: The inclusion criteria for Aim 3 consists of:

1. 18 years or older
2. Authorized as a professional to work at an OAT delivery site

Exclusion Criteria:

* Not willing to provide consent

Where it's running

• Columbia University Global Health Research Center of Central Asia
  Almaty, Kazakhstan Recruiting
• Den Sooluk Nuru
  Bishkek, Kyrgyzstan Recruiting
• Institute for International Health and Education
  Dushanbe, Tajikistan Recruiting
• Yale University
  New Haven, Connecticut, United States Active not recruiting

Study contacts

• Principal investigator: Frederick L Altice, MD — Yale University
• Study coordinator: Frederick L Altice, MD
• Email: frederick.altice@yale.edu
• Phone: 203-623-2634

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.