Exergame combined physical-and-cognitive training for 50–60-year-olds with subjective memory decline in China
Exergame-assisted Simultaneous Motor-cognitive Training for Middle-aged Old Adults in China: a Feasibility and Pilot Randomized Controlled Trail Study
NA · The Hong Kong Polytechnic University · NCT07085663
This pilot will test whether an exercise video game that combines physical and thinking tasks can improve movement, thinking, and doing both at once in Chinese adults aged 50–60 who notice memory decline.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 50 Years to 60 Years |
| Sex | All |
| Sponsor | The Hong Kong Polytechnic University (other) |
| Locations | 1 site (Chengdu, Sichuan) |
| Trial ID | NCT07085663 on ClinicalTrials.gov |
What this trial studies
This pilot will develop and deliver an exergame-assisted program that has participants perform motor and cognitive tasks at the same time using technology-based exercises. It will recruit adults aged 50–60 in mainland China who report subjective cognitive decline and will use the MoCA to exclude mild cognitive impairment. The study will measure feasibility (adherence, safety, and acceptability) and estimate preliminary effects on physical performance, cognitive test scores, and dual-task ability. Results will be used to refine the intervention and plan larger controlled trials.
Who should consider this trial
Good fit: Ideal candidates are adults aged 50–60 living in mainland China who meet the SCD-9 criteria for subjective cognitive decline, do not meet criteria for mild cognitive impairment on the MoCA, and are medically able to exercise.
Not a fit: People with diagnosed mild cognitive impairment or dementia, major cardiovascular, respiratory, metabolic, musculoskeletal, or neurological conditions that limit exercise, those outside the 50–60 age range, or those unable to attend in-person sessions are unlikely to benefit.
Why it matters
Potential benefit: If successful, the program could improve everyday mobility and cognitive performance and help delay decline in people noticing early memory problems.
How similar studies have performed: Previous small studies of exergames and combined motor–cognitive training in older adults have reported promising but preliminary improvements in cognition and physical function, so evidence remains supportive but not definitive.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * people between 50 and 60 years of age * living in mainland China * confirmed subjective cognitive decline with the following diagnostic criteria; a confirmed case of subjective cognitive decline that meets the subjective cognitive decline-9 scale and an exclusion of mild cognitive impairment cases using the Montreal Cognitive Assessment scale to rule out mild cognitive impairment; subjective decline in memory rather than other cognitive domains; episodes of subjective cognitive decline within the past 5 years; participants perceived to experience a sustained decline in cognitive performance compared to previous normality, independent of an acute event. * the absence of a medical condition that renders exercise inappropriate. This includes, but is not limited to, heart disease, hypertension, diabetes, respiratory disease (e.g., chronic obstructive pulmonary disease), joint and bone disease, and neurological disease (e.g., parkinson's disease) * have the ability to perform independent activities of daily living (as measured by the independent activities of daily living scale) * have no history of falls * have no language barriers and have adequate communication skills Exclusion Criteria: * active mental disorder, serious mental illness, neurological disorder, or cognitive impairment (standard mild cognitive impairment, prodromal Alzheimer's disease or dementia, or other significant cognitive deficits) * substance use for a long-term mental or neurological illness * severe mobility or sensory impairments that may prevent participation in research activities * unstable or acute medical conditions * individuals who have recently undergone major surgery or have acute orthopedic conditions * individuals who refuse to participate
Where this trial is running
Chengdu, Sichuan
- Sichuan Tianfu New District Huayang Street Helin Community Cognitive Care Center — Chengdu, Sichuan, China (RECRUITING)
Study contacts
- Study coordinator: Yaqin Li
- Email: yaqinli0809@gmail.com
- Phone: +86 18502853115
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Subjective Cognitive Decline, exergame, subjective cognitive decline, middle-aged, physical performance, cognitive performance, dual-task performance