Exergame combined physical-and-cognitive training for 50–60-year-olds with subjective memory decline in China
Official title: Exergame-assisted Simultaneous Motor-cognitive Training for Middle-aged Old Adults in China: a Feasibility and Pilot Randomized Controlled Trail Study
Run by The Hong Kong Polytechnic University · NCT07085663 · Data updated 2026-11-12
This pilot will test whether an exercise video game that combines physical and thinking tasks can improve movement, thinking, and doing both at once in Chinese adults aged 50–60 who notice memory decline.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 60 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Chengdu, Sichuan) |
| Status | Recruiting |
| Started | May 20, 2025 |
| Main results expected | August 30, 2025 |
| Study ends | August 30, 2025 |
| Registry record updated | July 25, 2025 |
| Trial ID | NCT07085663 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 50–60 living in mainland China who meet the SCD-9 criteria for subjective cognitive decline, do not meet criteria for mild cognitive impairment on the MoCA, and are medically able to exercise.
✕Probably not a fit
People with diagnosed mild cognitive impairment or dementia, major cardiovascular, respiratory, metabolic, musculoskeletal, or neurological conditions that limit exercise, those outside the 50–60 age range, or those unable to attend in-person sessions are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot will develop and deliver an exergame-assisted program that has participants perform motor and cognitive tasks at the same time using technology-based exercises. It will recruit adults aged 50–60 in mainland China who report subjective cognitive decline and will use the MoCA to exclude mild cognitive impairment. The study will measure feasibility (adherence, safety, and acceptability) and estimate preliminary effects on physical performance, cognitive test scores, and dual-task ability. Results will be used to refine the intervention and plan larger controlled trials.
Why it matters
Potential benefit: If successful, the program could improve everyday mobility and cognitive performance and help delay decline in people noticing early memory problems.
How similar studies have gone: Previous small studies of exergames and combined motor–cognitive training in older adults have reported promising but preliminary improvements in cognition and physical function, so evidence remains supportive but not definitive.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * people between 50 and 60 years of age * living in mainland China * confirmed subjective cognitive decline with the following diagnostic criteria; a confirmed case of subjective cognitive decline that meets the subjective cognitive decline-9 scale and an exclusion of mild cognitive impairment cases using the Montreal Cognitive Assessment scale to rule out mild cognitive impairment; subjective decline in memory rather than other cognitive domains; episodes of subjective cognitive decline within the past 5 years; participants perceived to experience a sustained decline in cognitive performance compared to previous normality, independent of an acute event. * the absence of a medical condition that renders exercise inappropriate. This includes, but is not limited to, heart disease, hypertension, diabetes, respiratory disease (e.g., chronic obstructive pulmonary disease), joint and bone disease, and neurological disease (e.g., parkinson's disease) * have the ability to perform independent activities of daily living (as measured by the independent activities of daily living scale) * have no history of falls * have no language barriers and have adequate communication skills Exclusion Criteria: * active mental disorder, serious mental illness, neurological disorder, or cognitive impairment (standard mild cognitive impairment, prodromal Alzheimer's disease or dementia, or other significant cognitive deficits) * substance use for a long-term mental or neurological illness * severe mobility or sensory impairments that may prevent participation in research activities * unstable or acute medical conditions * individuals who have recently undergone major surgery or have acute orthopedic conditions * individuals who refuse to participate
Where it's running
-
Sichuan Tianfu New District Huayang Street Helin Community Cognitive Care Center
Chengdu, Sichuan, China Recruiting
Study contacts
- Study coordinator: Yaqin Li
- Email: yaqinli0809@gmail.com
- Phone: +86 18502853115
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.