Exercise training for people with myeloproliferative neoplasms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, monocenter study assigns adults with myeloproliferative neoplasms to either a tailored exercise program for 12 weeks or a usual-care waiting period, with cross-over access after the control phase. Researchers measure physical performance, daily activity, strength, and patient-reported outcomes at the start and end of the intervention. The primary endpoint is watts at the respiratory compensation point, a submaximal fitness marker, with online monitoring and biweekly feedback during training. Blinded assessors help prevent bias during performance testing. The goal is to determine whether structured exercise can improve fitness and quality of life in MPN patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age ≥ 18 years
* diagnosis of myeloproliferative neoplasia according to WHO/ICC 2022.

Exclusion Criteria:

* current participation in another intervention study
* the presence of any diseases or functional impairments that, in the opinion of the examining physician, exclude participation in a physical training intervention.

Where it's running

• Hannover Medical School
  Hanover, Lower Saxony, Germany Recruiting
• Hannover Medical School
  Hanover, Lower Saxony, Germany Not yet recruiting

Study contacts

• Principal investigator: Uwe Tegtbur, Prof. Dr. — Hannover Medical School
• Study coordinator: Sven Haufe, Prof. Dr.
• Email: haufe.sven@mh-hannover.de
• Phone: +49 511 532 5499

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Orally administered JBI-802 in certain blood cancers with high platelets

  This study tests whether taking JBI-802 by mouth can be safe and helpful for adults with essential thrombocythemia or related blood cancers that involve high platelet counts.

  Recruiting at 7 sites Phase 1/2 Jubilant Therapeutics Inc. · Sydney, New South Wales and 6 other locations · NCT07612280

• Comparing daily aspirin doses in high-risk MPN patients with aspirin resistance

  This study is testing whether taking aspirin once a day or twice a day can help high-risk patients with blood disorders reduce the risk of blood clots.

  Recruiting Phase 3 Siriraj Hospital · Bangkok Noi, Bangkok · NCT06740916

• Direct auditory nerve stimulation to see if it can evoke loudness and pitch in adults with severe deafness

  This study tests whether direct stimulation of the auditory nerve with a nerve implant can produce clear loudness and pitch perceptions in adults who can’t use standard cochlear implants.

  Recruiting Hannover Medical School · Hanover and 1 other locations · NCT07789665

• Everolimus-based calcineurin-free immunosuppression one year after liver transplant

  This trial tests whether switching to or using everolimus with reduced calcineurin inhibitors after year one post-liver transplant can protect kidney function while maintaining graft health in adults at low rejection risk.

  Recruiting Phase 3 Hannover Medical School · Heidelberg, Baden-Wurttemberg and 15 other locations · NCT07739914

• I-scoop vs C-Mac D-Blade for airway management with spontaneous breathing

  This study tests whether the i-scoop videolaryngoscope makes airway management with the patient breathing on their own and light sedation easier and safer than the C-Mac D-Blade in adults having surgery under general anesthesia.

  Recruiting Hannover Medical School · Hanover, Lower Saxony · NCT07624162

• PARO robotic seal to reduce agitation after visceral surgery

  This trial tests whether interacting with PARO, a social robotic seal, reduces postoperative agitation in adults having elective visceral surgery.

  Recruiting Hannover Medical School · Hanover, Lower Saxony · NCT07568093

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.