Exercise training effects on frailty and fall risk in chronic heart failure patients
Official title: The Effect of Exercise Training Intervention and Detraining on Frailty and Fall Risk in Patients With Chronic Heart Failure.
Run by Aristotle University Of Thessaloniki · NCT06036615 · Data updated 2026-11-12
This study is testing if exercise training can help people with chronic heart failure feel stronger and reduce their risk of falling.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Aristotle University Of Thessaloniki Academic / other |
| Locations | 1 site (Thessaloniki, Thermi) |
| Status | Recruiting |
| Started | October 1, 2023 |
| Main results expected | September 30, 2025 |
| Study ends | December 15, 2025 |
| Registry record updated | August 11, 2025 |
| Trial ID | NCT06036615 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with a confirmed diagnosis of chronic heart failure and classified as NYHA class II-III.
✕Probably not a fit
Patients with acute myocardial infarction, severe valvular diseases, or those unable to participate in exercise due to neurological or orthopedic limitations may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of exercise training on frailty and fall risk in patients suffering from chronic heart failure (CHF). It aims to assess how structured exercise interventions can improve functional capacity and quality of life in individuals with CHF, particularly those classified as symptomatic New York Heart Association (NYHA) class II-III. The study will include patients diagnosed with either heart failure with reduced or preserved ejection fraction and will monitor their progress through the exercise program. The findings could provide insights into non-pharmacological treatments for frailty associated with CHF.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for frailty in chronic heart failure patients, enhancing their quality of life and reducing fall risk.
How similar studies have gone: Previous studies have shown promising results for exercise interventions in improving outcomes for patients with chronic heart failure, suggesting that this approach is both viable and beneficial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 yrs. of either gender * Confirmed diagnosis (by echocardiography) of HF reduced or preserved left ventricular ejection fraction (HFrEF/ΗFpEF) * Symptomatic New York Heart Association (NYHA) class II-III Exclusion Criteria: * Acute Myocardial Infarction (\<4 weeks) * Severe valvular diseases * Potentially malignant arrhythmias * Νeurological, or orthopedic limitations/non- ambulant status * Cognitive disorders * Poor regulation of comorbidities * Already participating in organized exercise programs * Current pregnancy * NYHA function class IV * Inability/unwillingness to give informed consent
Where it's running
-
Sports Medicine Laboratory, Aristotle University of Thessaloniki
Thessaloniki, Thermi, Greece Recruiting
Study contacts
- Study coordinator: Evangelia Kouidi, Professor
- Email: kouidi@phed.auth.gr
- Phone: +302310992189
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.