Exercise training effects on frailty and fall risk in chronic heart failure patients
The Effect of Exercise Training Intervention and Detraining on Frailty and Fall Risk in Patients With Chronic Heart Failure.
This study is testing if exercise training can help people with chronic heart failure feel stronger and reduce their risk of falling.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Aristotle University Of Thessaloniki Academic / other |
| Locations | 1 site (Thessaloniki, Thermi) |
| Trial ID | NCT06036615 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of exercise training on frailty and fall risk in patients suffering from chronic heart failure (CHF). It aims to assess how structured exercise interventions can improve functional capacity and quality of life in individuals with CHF, particularly those classified as symptomatic New York Heart Association (NYHA) class II-III. The study will include patients diagnosed with either heart failure with reduced or preserved ejection fraction and will monitor their progress through the exercise program. The findings could provide insights into non-pharmacological treatments for frailty associated with CHF.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with a confirmed diagnosis of chronic heart failure and classified as NYHA class II-III.
Not a fit: Patients with acute myocardial infarction, severe valvular diseases, or those unable to participate in exercise due to neurological or orthopedic limitations may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for frailty in chronic heart failure patients, enhancing their quality of life and reducing fall risk.
How similar studies have performed: Previous studies have shown promising results for exercise interventions in improving outcomes for patients with chronic heart failure, suggesting that this approach is both viable and beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 yrs. of either gender * Confirmed diagnosis (by echocardiography) of HF reduced or preserved left ventricular ejection fraction (HFrEF/ΗFpEF) * Symptomatic New York Heart Association (NYHA) class II-III Exclusion Criteria: * Acute Myocardial Infarction (\<4 weeks) * Severe valvular diseases * Potentially malignant arrhythmias * Νeurological, or orthopedic limitations/non- ambulant status * Cognitive disorders * Poor regulation of comorbidities * Already participating in organized exercise programs * Current pregnancy * NYHA function class IV * Inability/unwillingness to give informed consent
Where this trial is running
Thessaloniki, Thermi
- Sports Medicine Laboratory, Aristotle University of Thessaloniki — Thessaloniki, Thermi, Greece (Recruiting)
Study contacts
- Study coordinator: Evangelia Kouidi, Professor
- Email: kouidi@phed.auth.gr
- Phone: +302310992189
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.