Exercise to Reduce PreEclampsia Risk in Pregnant Women
Physical Activity to Mitigate PreEclampsia Risk (PAMPER)
NA · East Carolina University · NCT06319014
This study is testing whether different types of exercise can help pregnant women at risk for preeclampsia have healthier pregnancies and better outcomes for their babies.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 224 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | East Carolina University (other) |
| Locations | 1 site (Greenville, North Carolina) |
| Trial ID | NCT06319014 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effects of different types of exercise—aerobic, resistance, and a combination of both—on maternal and fetal health in women at risk for preeclampsia. The researchers will assess how these exercise modes influence maternal cardiometabolic health and birth outcomes throughout pregnancy. By monitoring various physiological variables, the study seeks to determine which exercise regimen is most effective in reducing the severity and occurrence of preeclampsia symptoms. The ultimate goal is to improve health outcomes for both mothers and their infants.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy women aged 18-40 years, less than 16 weeks pregnant, with a singleton pregnancy and a BMI between 18.5 and 45.0.
Not a fit: Patients with pre-existing chronic conditions or those taking medications that affect fetal development may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved health outcomes for pregnant women and their infants by reducing the risk and severity of preeclampsia.
How similar studies have performed: Preliminary data from other studies suggest that exercise may help mitigate the severity and risk of preeclampsia, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * healthy women, age 18-40 years, \<16 weeks' gestation, with singleton pregnancy; women (BMI:18.5-45.0), sedentary, cleared by their obstetric provider. Exclusion Criteria: * pre-existing chronic conditions such as HIV, lupus, etc.; taking medicines that affect fetal development; and/or lack of telephone or email contact information).
Where this trial is running
Greenville, North Carolina
- East Carolina University — Greenville, North Carolina, United States (RECRUITING)
Study contacts
- Principal investigator: Linda E May, MS, PhD — East Carolina University
- Study coordinator: Linda E May, MS, PhD
- Email: mayl@ecu.edu
- Phone: 2527377072
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pre-Eclampsia