Exercise to Reduce PreEclampsia Risk in Pregnant Women
Official title: Physical Activity to Mitigate PreEclampsia Risk (PAMPER)
Run by East Carolina University · NCT06319014 · Data updated 2026-11-12
This study is testing whether different types of exercise can help pregnant women at risk for preeclampsia have healthier pregnancies and better outcomes for their babies.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 224 (estimated) |
| Sponsor | East Carolina University Academic / other |
| Locations | 1 site (Greenville, North Carolina) |
| Status | Recruiting |
| Started | June 24, 2024 |
| Main results expected | December 1, 2027 |
| Study ends | December 1, 2027 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT06319014 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy women aged 18-40 years, less than 16 weeks pregnant, with a singleton pregnancy and a BMI between 18.5 and 45.0.
✕Probably not a fit
Patients with pre-existing chronic conditions or those taking medications that affect fetal development may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the effects of different types of exercise—aerobic, resistance, and a combination of both—on maternal and fetal health in women at risk for preeclampsia. The researchers will assess how these exercise modes influence maternal cardiometabolic health and birth outcomes throughout pregnancy. By monitoring various physiological variables, the study seeks to determine which exercise regimen is most effective in reducing the severity and occurrence of preeclampsia symptoms. The ultimate goal is to improve health outcomes for both mothers and their infants.
Why it matters
Potential benefit: If successful, this study could lead to improved health outcomes for pregnant women and their infants by reducing the risk and severity of preeclampsia.
How similar studies have gone: Preliminary data from other studies suggest that exercise may help mitigate the severity and risk of preeclampsia, indicating potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * healthy women, age 18-40 years, \<16 weeks' gestation, with singleton pregnancy; women (BMI:18.5-45.0), sedentary, cleared by their obstetric provider. Exclusion Criteria: * pre-existing chronic conditions such as HIV, lupus, etc.; taking medicines that affect fetal development; and/or lack of telephone or email contact information).
Where it's running
-
East Carolina University
Greenville, North Carolina, United States Recruiting
Study contacts
- Principal investigator: Linda E May, MS, PhD — East Carolina University
- Study coordinator: Linda E May, MS, PhD
- Email: mayl@ecu.edu
- Phone: 2527377072
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.