Exercise therapy before and after stenting for leg artery disease
Prehabilitation and Rehabilitation in PAD: A Randomized Exercise Intervention Trial (PREPARE-IT)
NA · Palo Alto Veterans Institute for Research · NCT06566976
This study tests whether exercise programs before and after stenting can help people with leg artery disease feel better and recover faster.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Palo Alto Veterans Institute for Research (other) |
| Locations | 1 site (Palo Alto, California) |
| Trial ID | NCT06566976 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of prehabilitation and rehabilitation exercise programs for patients with peripheral artery disease (PAD) who are scheduled to undergo stenting. It aims to improve patients' exercise tolerance and lifestyle factors before the procedure, potentially leading to fewer complications and a quicker recovery. Participants will engage in a structured exercise regimen designed to enhance their overall health and ability to perform daily activities. The study will assess the impact of these interventions on pain management and quality of life post-surgery.
Who should consider this trial
Good fit: Ideal candidates include adults diagnosed with PAD who experience leg pain while walking and are scheduled for a stent procedure.
Not a fit: Patients who are medically unstable, have had a recent heart attack, or have uncontrolled diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve recovery outcomes and quality of life for patients with peripheral artery disease.
How similar studies have performed: Previous studies have shown that exercise-based rehabilitation can greatly benefit patients with PAD, indicating a promising approach for this intervention.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or Female adult diagnosed with peripheral artery disease (PAD) * Experiencing leg pain while walking * Scheduled to have a stent for PAD * Able to perform exercise safely * Postmenopausal and not of child bearing capacity Exclusion Criteria: * Medically unstable patients * Recent MI within 3 months * Malignancy * Uncontrolled diabetes mellitus (HBA1C ≥8 mmol/l) * Alcoholism or other recreational drug use
Where this trial is running
Palo Alto, California
- VA Palo Alto Health Care System — Palo Alto, California, United States (RECRUITING)
Study contacts
- Study coordinator: Jonathan N Myers, PhD
- Email: drj993@aol.com
- Phone: 650-493-5000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Peripheral Arterial Disease