Exercise test to help predict outcomes in adults with flu-like symptoms, comparing vaccinated and unvaccinated people
Can the Ergometric Test in Flu-like Syndrome Help in the Outcome Analysis of Unvaccinated Patients
This project will test whether measuring blood pressure and heart rhythm during an exercise (ergometric) test can help predict 30-day outcomes for adults with flu-like symptoms, comparing vaccinated and unvaccinated people.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Sao Paulo Academic / other |
| Locations | 1 site (São Paulo, São Paulo) |
| Trial ID | NCT07007377 on ClinicalTrials.gov |
What this trial studies
This observational study enrolls adults who present with flu-like symptoms and are already indicated for an ergometric (exercise) test. Investigators record vaccination history, perform the exercise test, and measure hemodynamic responses such as blood pressure changes, arrhythmias, ischemia, and test duration. Participants are followed for 30 days after the test to record outcomes and any cardiovascular events. Patients with recent orthopedic surgery are excluded and the work is conducted at Clínica Pró-Coração in São Paulo under the University of São Paulo.
Who should consider this trial
Good fit: Adults with current flu-like symptoms who are referred for an ergometric (exercise) test and have no recent orthopedic surgery.
Not a fit: People who are not cleared for exercise testing, have recent orthopedic surgery, or cannot attend the clinic are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, this approach could help clinicians better identify patients at higher short-term cardiovascular risk during flu-like illness and guide monitoring or treatment.
How similar studies have performed: Exercise test hemodynamics have been used to predict cardiovascular risk in other settings, but applying ergometric testing specifically during acute flu-like illness is relatively novel and not well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * flu-symptoms Exclusion Criteria: * recent orthopedic surgery
Where this trial is running
São Paulo, São Paulo
- Clínica Pró-Coração — São Paulo, São Paulo, Brazil (Recruiting)
Study contacts
- Study coordinator: Pedro GS Braga, PhD
- Email: pedro.senger@gmail.com
- Phone: 5511941044044
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.