Exercise rehabilitation for patients with pulmonary artery disease
Effects of Exercise-based Rehabilitation on Exercise Capacity, Quality of Life and Physical Activity in Patients With Pulmonary Artery Disease
NA · Tampere Heart Hospital · NCT06804122
This study is testing a group exercise program to see if it can help people with pulmonary arterial hypertension feel better and be more active.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tampere Heart Hospital (other) |
| Locations | 1 site (Tampere, Pirkanmaa) |
| Trial ID | NCT06804122 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of a group-based outpatient exercise rehabilitation program on patients with pulmonary arterial hypertension (PAH). It aims to improve exercise capacity, quality of life, and physical activity levels among participants, following the European guidelines that recommend exercise as part of PAH treatment. The rehabilitation will be supervised by experienced professionals and tailored to fit the Finnish healthcare system. The study addresses the lack of specific outpatient exercise guidelines for PAH patients, focusing on a safe and effective rehabilitation model.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with stable PAH, classified as WHO functional class II-III, residing in Tampere or nearby municipalities.
Not a fit: Patients with severe pulmonary disease, significant heart conditions, or other serious health issues that limit physical capacity may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly enhance the quality of life and functional capacity of patients with pulmonary arterial hypertension.
How similar studies have performed: While studies on exercise rehabilitation for PAH patients are limited, existing multicenter studies have shown positive outcomes, indicating potential success for this outpatient approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults over 18 years old residing in Tampere or nearby municipalities. * WHO functional classification II-III. * Commitment to the exercise program. * Stable disease condition with no PAH medication changes in the two months prior. * No recent syncope or arrhythmias causing symptoms within the past two months. Exclusion Criteria: * Severe pulmonary disease or left ventricular failure (HFrEF). * Pregnancy. * Severe congenital heart defect (Eisenmenger syndrome). * Severe liver disease. * Acute inflammatory condition. * Severe anemia (hemoglobin ≤ 75% of the lower reference limit). * Systolic blood pressure below 85 mmHg. * Recent syncope. * Other significant conditions affecting physical capacity, such as severe neurological diseases or musculoskeletal issues. * Untreated severe arrhythmias. * Changes in PAH medication during the rehabilitation program.
Where this trial is running
Tampere, Pirkanmaa
- Tampere Heart Hospital — Tampere, Pirkanmaa, Finland (RECRUITING)
Study contacts
- Study coordinator: Pauliina Leskelä, MD
- Email: pauliina.leskela@sydansairaala.fi
- Phone: +3583311611
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Arterial Hypertension, Exercise-based rehabilitation, Intervention