Exercise program to improve recovery for head and neck cancer surgery patients

The Effect of Exercise Prehabilitation on Post-Operative Recovery After Head and Neck Cancer Surgery

Not applicable Interventional OHSU Knight Cancer Institute · NCT06079697

This study tests whether a special exercise program before surgery can help head and neck cancer patients recover better and feel stronger afterwards.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 89 Years
SexAll
SponsorOHSU Knight Cancer Institute Academic / other
Locations1 site (Portland, Oregon)
Trial IDNCT06079697 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates a prehabilitation exercise intervention aimed at enhancing mobility and recovery outcomes for patients undergoing surgery for head and neck cancer. The intervention includes a daily walking program, sit-to-stand training, and standing therapeutic exercises, which patients will engage in before their surgery. The study will assess the impact of this exercise regimen on post-operative outcomes, including weight loss, depression, and overall recovery. Patients will be monitored using wearable devices to track their activity levels throughout the process.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 89 who are scheduled for major head and neck cancer surgery with free tissue transfer reconstruction.

Not a fit: Patients who are non-English speaking, have planned ICU admissions, or possess conditions that may hinder safe exercise will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve recovery times and quality of life for patients after head and neck cancer surgery.

How similar studies have performed: Other studies have shown positive outcomes with prehabilitation approaches in surgical recovery, suggesting this intervention may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Older than 18 years of age and younger than 89 years of age. Both men and women and members of all races and ethnic groups may be included
* Planned to undergo major head and neck cancer surgery with free tissue transfer reconstruction at Oregon Health and Science University (OHSU) with the Department of Otolaryngology-Head and Neck Surgery with an expected length of stay (LOS) of 3 days or more
* Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

* Non-English speaking
* Planned postoperative admission to the intensive care unit (ICU)
* Social or psychiatric conditions that may interfere with compliance
* Further exclusion criteria may be applied due to conditions that may impact the ability to safely exercise as well as utilize the Fitbit devices:
* Symptoms of or ongoing work-up for unstable angina, uncontrolled tachyarrhythmias, decompensated heart failure, severe aortic stenosis, hypertrophic obstructive cardiomyopathy, uncontrolled hypertension (HTN), uncontrolled pulmonary HTN or uncontrolled asthma
* History of chest pain, dizziness or syncope with exercise
* Bony metastases to the spine or extremities
* Falls in the last year
* Cognitive impairments limiting safety or ability to use technology
* Impaired mobility requiring the use of assistive devices, such as use of a walker or wheelchair at baseline
* Isolation precautions, as they would not be allowed to ambulate on a patient floor post-operatively

Where this trial is running

Portland, Oregon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Head and Neck Carcinoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.