Exercise program to improve arteriovenous fistula maturation
Benefits of a Perioperative Exercise Program on Maturation of Dialysis Arteriovenous Fistulas
This study is testing if a handgrip exercise program can help improve the development of arteriovenous fistulas in patients with chronic kidney disease who are getting ready for hemodialysis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Pierre-Bénite) |
| Trial ID | NCT04034433 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of a perioperative handgrip training program on the maturation of arteriovenous fistulas (AVF) in patients with chronic kidney disease (CKD) who are preparing for hemodialysis. The program aims to enhance the diameter of the AVF, which is crucial for successful vascular access. Participants will engage in a structured handgrip exercise regimen to assess its impact on AVF outcomes. The study is conducted at the University Hospital of Lyon Sud, focusing on patients with advanced CKD.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with chronic kidney disease (eGFR <30 mL/min) who have chosen hemodialysis as their treatment.
Not a fit: Patients with contraindications for AVF surgery, prior vascular access, or those unable to perform handgrip exercises may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could lead to improved maturation rates of arteriovenous fistulas, enhancing dialysis access and patient outcomes.
How similar studies have performed: While the specific approach of handgrip training for AVF maturation is novel, similar exercise interventions have shown promise in improving vascular access outcomes in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients older than 18 years * with chronic kidney disease (Estimated Glomerular Filtration Rate (eGFR) \<30 milliLiter/minute (mL/min)) * with follow-up at the University Hospital of Lyon Sud * who choose hemodialysis as renal replacement therapy Exclusion Criteria: * contraindication for arteriovenous fistula (AVF) surgery * refusing AVF creation * prior vascular access * antecedent of IV substance abuse * active cancer * inability to perform handgrip exercise * physical or mental disability limiting follow-up possibility * inclusion in an other interventional study * no social welfare
Where this trial is running
Pierre-Bénite
- Service de néphrologie, dialyse et nutrition rénale - Centre Hospitalier Lyon Sud — Pierre-Bénite, France (Recruiting)
Study contacts
- Principal investigator: Abbas DEEB, PhD — Hospices Civils de Lyon
- Study coordinator: Abbas DEEB, PhD
- Email: abbas.deeb@chu-lyon.fr
- Phone: 04.72.67.87.03
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.