Exercise program for kidney transplant candidates
Virtually Supervised Exercise for Kidney Transplant Candidates
This study is testing whether a virtual exercise program can help people waiting for a kidney transplant feel stronger and less tired compared to those who only get health education.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Stanford University Academic / other |
| Locations | 1 site (Palo Alto, California) |
| Trial ID | NCT05355545 on ClinicalTrials.gov |
What this trial studies
This study examines the effectiveness of a virtually supervised exercise program aimed at improving physical function in individuals awaiting kidney transplants. It is a double-blind, parallel group randomized controlled trial enrolling 80 participants over 24 weeks. The primary outcome measured will be performance on the 30-second sit-to-stand test, while secondary outcomes include changes in fatigue and depression levels. Participants will be compared to a control group receiving a health education program.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are listed for a kidney transplant and experience physical difficulties related to mobility.
Not a fit: Patients who do not speak English or have severe sensory impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could enhance physical function and overall well-being for patients awaiting kidney transplants.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions for patients with similar conditions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥ 18 years old * Listed for kidney transplant * Positive answers (e.g. yes) to one of the following: * current difficulty with climbing up 10 stairs, * has changed in the past year how they climb 10 stairs * current difficulty with walking a 0.5 mile (5-6 blocks) * has changed in past year in how they walk 0.5 mile (5-6 blocks) * documented performance of 430 meters or less on the six minute walk test in the past 12 months * documented performance of 9 points or less on the Short Physical Performance Battery in the past 24 months * documented performance of less than 3 points or less on the five times sit to stand test in the past 24 months * Demonstrated ability to stand up independently from a seated position and then sit back down without using their arms or an assistive device in the past 24 months Exclusion Criteria: * Does not speak English * Nursing home resident * Severe low vision (≥20/200 with corrective lens) * Severe hearing loss even with use of amplification preventing communication * Unstable angina or uncontrolled arrhythmia * Supplemental oxygen therapy * Myocardial infarction, major heart surgery, stroke, venous thromboembolism, hip fracture, hip or knee replacement in past six months (temporary exclusion) * ≥ 3 errors on the Six Item Screener
Where this trial is running
Palo Alto, California
- Stanford University — Palo Alto, California, United States (Recruiting)
Study contacts
- Study coordinator: Christine K Liu, MD
- Email: kidneystudy@stanford.edu
- Phone: 650-723-1365
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.