Clinical trial No longer in our active list Interventional Ages 18 to 100

Exercise program for kidney transplant candidates

Official title: Virtually Supervised Exercise for Kidney Transplant Candidates

Run by Stanford University · NCT05355545 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing whether a virtual exercise program can help people waiting for a kidney transplant feel stronger and less tired compared to those who only get health education.

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment80 (estimated)
SponsorStanford University
Academic / other
Locations1 site (Palo Alto, California)
Trial IDNCT05355545 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are listed for a kidney transplant and experience physical difficulties related to mobility.

Probably not a fit

Patients who do not speak English or have severe sensory impairments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the effectiveness of a virtually supervised exercise program aimed at improving physical function in individuals awaiting kidney transplants. It is a double-blind, parallel group randomized controlled trial enrolling 80 participants over 24 weeks. The primary outcome measured will be performance on the 30-second sit-to-stand test, while secondary outcomes include changes in fatigue and depression levels. Participants will be compared to a control group receiving a health education program.

Why it matters

Potential benefit: If successful, this program could enhance physical function and overall well-being for patients awaiting kidney transplants.

How similar studies have gone: Other studies have shown positive outcomes with exercise interventions for patients with similar conditions, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 18 years old
* Listed for kidney transplant
* Positive answers (e.g. yes) to one of the following:

  * current difficulty with climbing up 10 stairs,
  * has changed in the past year how they climb 10 stairs
  * current difficulty with walking a 0.5 mile (5-6 blocks)
  * has changed in past year in how they walk 0.5 mile (5-6 blocks)
  * documented performance of 430 meters or less on the six minute walk test in the past 12 months
  * documented performance of 9 points or less on the Short Physical Performance Battery in the past 24 months
  * documented performance of less than 3 points or less on the five times sit to stand test in the past 24 months
* Demonstrated ability to stand up independently from a seated position and then sit back down without using their arms or an assistive device in the past 24 months

Exclusion Criteria:

* Does not speak English
* Nursing home resident
* Severe low vision (≥20/200 with corrective lens)
* Severe hearing loss even with use of amplification preventing communication
* Unstable angina or uncontrolled arrhythmia
* Supplemental oxygen therapy
* Myocardial infarction, major heart surgery, stroke, venous thromboembolism, hip fracture, hip or knee replacement in past six months (temporary exclusion)
* ≥ 3 errors on the Six Item Screener

Where it's running

  • Stanford University
    Palo Alto, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.